Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 5/20 | 0.69 |
| ▸ | CXCR2 | P25025 | 5/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.66 |
| ▸ | ALB | P02768 | 1/20 | 0.66 |
| ▸ | ESR1 | P03372 | 1/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.66 |
| ▸ | RARB | P10826 | 1/20 | 0.66 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.66 |
| ▸ | HTR2A | P28223 | 1/20 | 0.66 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.66 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.66 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.66 |
| ▸ | BLM | P54132 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8001977 | 1.00 | CXCR1 (0.69) | CXCR1CXCR2PTGS2PTGS1LMNA | |
| SCHEMBL8754792 | 1.00 | CXCR1 (0.69) | CXCR1CXCR2PTGS2PTGS1LMNA | |
| SCHEMBL9086058 | 1.00 | CXCR1 (0.69) | CXCR1CXCR2PTGS2PTGS1LMNA | |
| Water SCHEMBL11489033 | 0.98 | CXCR1 (0.67) | CXCR1CXCR2PTGS2PTGS1LMNA | |
| SCHEMBL9111108 | 0.87 | PTGS2 (0.68) | CXCR1CXCR2PTGS2PTGS1LMNA | |
| SCHEMBL16375965 | 0.86 | PTGS2 (0.66) | CXCR1CXCR2PTGS2PTGS1LMNA | |
| SCHEMBL17464177 | 0.86 | PTGS2 (0.66) | CXCR1CXCR2PTGS2PTGS1LMNA | |
| SCHEMBL12896272 | 0.86 | PTGS2 (0.66) | CXCR1CXCR2PTGS2PTGS1LMNA | |
| SCHEMBL24858354 | 0.84 | CXCR1 (0.58) | CXCR1CXCR2PTGS2PTGS1LMNA | |
| SCHEMBL2944919 | 0.84 | PTGS2 (0.64) | CXCR1CXCR2PTGS2PTGS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003216-B | Preparation method of ibuprofen | 沈阳药科大学 | 2024-08-06 | — | — | CN | claimed |
| CN-113862117-B | Device and method for separating chiral substances by multi-liquid-phase system continuous enzyme method | 华南理工大学 | 2024-03-12 | — | — | CN | claimed |
| CN-116003216-A | Preparation method of ibuprofen | 沈阳药科大学 | 2023-04-25 | — | — | CN | claimed |
| EP-2744771-B1 | C-HALOGEN BOND FORMATION | UNIV PRINCETON (US) | 2020-10-21 | — | — | EP | claimed |
| CN-108504618-B | Recombinant bacterium for expressing lipase with R configuration selectivity and application thereof | 华南理工大学 | 2020-08-18 | — | — | CN | claimed |
| US-20200190012-A1 | C-HALOGEN BOND FORMATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2020-06-18 | — | — | US | claimed |
| US-20200140290-A1 | Remediation of physiologically active compounds from waste water | SECURE NATURAL RESOURCES LLC (US) | 2020-05-07 | — | — | US | claimed |
| US-20190127311-A1 | C-HALOGEN BOND FORMATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2019-05-02 | — | — | US | claimed |
| US-10196341-B2 | C-halogen bond formation | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2019-02-05 | — | — | US | claimed |
| US-20160264512-A1 | C-HALOGEN BOND FORMATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2016-09-15 | — | — | US | claimed |
| US-20140249329-A1 | C-HALOGEN BOND FORMATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2014-09-04 | — | — | US | claimed |
| US-20140227184-A1 | C-HALOGEN BOND FORMATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2014-08-14 | — | — | US | claimed |
| EP-2744771-A1 | C-HALOGEN BOND FORMATION | The Trustees of Princeton University (US) | 2014-06-25 | — | — | EP | claimed |
| WO-2013081685-A1 | C-HALOGEN BOND FORMATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2013-06-06 | — | — | WO | claimed |
| US-8426630-B2 | Method and apparatus for continuous flow synthesis of ibuprofen | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2013-04-23 | — | — | US | claimed |
| EP-2580165-A1 | REMEDIATION OF PHYSIOLOGICALLY ACTIVE COMPOUNDS FROM WASTE WATER | Molycorp Minerals, LLC (US) | 2013-04-17 | — | — | EP | claimed |
| WO-2013028639-A1 | C-HALOGEN BOND FORMATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2013-02-28 | — | — | WO | claimed |
| US-20110054208-A1 | METHOD AND APPARATUS FOR CONTINUOUS FLOW SYNTHESIS OF IBUPROFEN | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2011-03-03 | — | — | US | claimed |
| US-5322791-A | Enantiospecific hydrolysis | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1994-06-21 | — | — | US | claimed |
| EP-0227078-A1 | Process for preparing (S)-alpha-methylarylacetic acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1987-07-01 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200190012-A1 | C-HALOGEN BOND FORMATION | CBR3, FOS, CBR1 | CXCR1 711/4885CXCR2 669/4885PTGS2 4205/4885 |
| US-20140227184-A1 | C-HALOGEN BOND FORMATION | CBR3, FOS, CBR1 | CXCR1 711/4885CXCR2 669/4885PTGS2 4205/4885 |
| US-20160264512-A1 | C-HALOGEN BOND FORMATION | FOS, BCL3, CBR3 | CXCR1 448/4885CXCR2 385/4885PTGS2 4494/4885 |
| US-20190127311-A1 | C-HALOGEN BOND FORMATION | CBR3, FOS, CBR1 | CXCR1 711/4885CXCR2 669/4885PTGS2 4205/4885 |
| US-20140249329-A1 | C-HALOGEN BOND FORMATION | CBR3, FOS, CBR1 | CXCR1 711/4885CXCR2 669/4885PTGS2 4205/4885 |
| US-10196341-B2 | C-halogen bond formation | CBR3, FOS, CBR1 | CXCR1 711/4885CXCR2 669/4885PTGS2 4205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.