Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 5/20 | 0.69 |
| ▸ | CXCR2 | P25025 | 5/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.66 |
| ▸ | ALB | P02768 | 1/20 | 0.66 |
| ▸ | ESR1 | P03372 | 1/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.66 |
| ▸ | RARB | P10826 | 1/20 | 0.66 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.66 |
| ▸ | HTR2A | P28223 | 1/20 | 0.66 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.66 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.66 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.66 |
| ▸ | BLM | P54132 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL576873 | 1.00 | CXCR1 (0.69) | CXCR1CXCR2PTGS2PTGS1LMNA | |
| SCHEMBL8754792 | 1.00 | CXCR1 (0.69) | CXCR1CXCR2PTGS2PTGS1LMNA | |
| SCHEMBL9086058 | 1.00 | CXCR1 (0.69) | CXCR1CXCR2PTGS2PTGS1LMNA | |
| Water SCHEMBL11489033 | 0.98 | CXCR1 (0.67) | CXCR1CXCR2PTGS2PTGS1LMNA | |
| SCHEMBL9111108 | 0.87 | PTGS2 (0.68) | CXCR1CXCR2PTGS2PTGS1LMNA | |
| SCHEMBL16375965 | 0.86 | PTGS2 (0.66) | CXCR1CXCR2PTGS2PTGS1LMNA | |
| SCHEMBL17464177 | 0.86 | PTGS2 (0.66) | CXCR1CXCR2PTGS2PTGS1LMNA | |
| SCHEMBL12896272 | 0.86 | PTGS2 (0.66) | CXCR1CXCR2PTGS2PTGS1LMNA | |
| SCHEMBL24858354 | 0.84 | CXCR1 (0.58) | CXCR1CXCR2PTGS2PTGS1LMNA | |
| SCHEMBL2944919 | 0.84 | PTGS2 (0.64) | CXCR1CXCR2PTGS2PTGS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250241921-A1 | ANTI-INFLAMMATORY COUPLING COMPOUND DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF | COVAL BIOPHARMA (SHANGHAI)CO., LTD. (CN) | 2025-07-31 | — | — | US | disclosed |
| US-20250241922-A1 | ANTI-INFLAMMATORY COUPLING COMPOUND DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF | COVAL BIOPHARMA (SHANGHAI)CO., LTD. (CN) | 2025-07-31 | — | — | US | disclosed |
| US-12290519-B2 | Anti-inflammatory coupling compound drug, and preparation method therefor and use thereof | COVAL BIOPHARMA (SHANGHAI) CO., LTD. (CN) | 2025-05-06 | — | — | US | disclosed |
| US-20240197741-A1 | EXTERNAL ANTI-INFLAMMATORY COUPLING COMPOUND DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF | COVAL BIOPHARMA(SHANGHAI)CO., LTD. (CN) | 2024-06-20 | — | — | US | disclosed |
| EP-4357346-A1 | EXTERNAL ANTI-INFLAMMATORY COUPLING COMPOUND DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Coval Biopharma (Shanghai) Co., Ltd. (CN) | 2024-04-24 | — | — | EP | disclosed |
| WO-2023001045-A9 | EXTERNAL ANTI-INFLAMMATORY COUPLING COMPOUND DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海椿安生物医药科技有限公司 | 2023-10-26 | — | — | WO | disclosed |
| WO-2023001045-A1 | EXTERNAL ANTI-INFLAMMATORY COUPLING COMPOUND DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海椿安生物医药科技有限公司 | 2023-01-26 | — | — | WO | disclosed |
| EP-2799422-B1 | METHOD FOR PRODUCING CARBOXYLIC ACID AND ALCOHOL BY HYDROLYSIS OF ESTER | UNIV NAGOYA NAT UNIV CORP (JP) | 2018-02-14 | — | — | EP | disclosed |
| US-9206107-B2 | Method for producing carboxylic acid and alcohol by hydrolysis of ester | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2015-12-08 | — | — | US | disclosed |
| US-9206107-B2 | Method for producing carboxylic acid and alcohol by hydrolysis of ester | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2015-12-08 | — | — | US | disclosed |
| US-20140378692-A1 | METHOD FOR PRODUCING CARBOXYLIC ACID AND ALCOHOL BY HYDROLYSIS OF ESTER | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-12-25 | — | — | US | disclosed |
| US-20140378692-A1 | METHOD FOR PRODUCING CARBOXYLIC ACID AND ALCOHOL BY HYDROLYSIS OF ESTER | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-12-25 | — | — | US | disclosed |
| US-7893094-B2 | Amphiphilic pyridinium compounds, method of making and use thereof | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (US) | 2011-02-22 | — | — | US | disclosed |
| US-20070105916-A1 | Amphiphilic pyridinium compounds, method of making and use thereof | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. | 2007-05-10 | — | — | US | disclosed |
| US-20070105916-A1 | Amphiphilic pyridinium compounds, method of making and use thereof | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. | 2007-05-10 | — | — | US | disclosed |
| US-6294573-B1 | FOR THERAPY RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, OSTEOPENIAS SUCH AS OSTEOPOROSIS, PERIODONTITIS, GINGIVITIS, CORNEAL, EPIDERMAL OR GASTRIC ULCERATION, AND TUMOR GROWTH AND METASTASIS OR INVASION | ABBOTT LABORATORIES | 2001-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250241921-A1 | ANTI-INFLAMMATORY COUPLING COMPOUND DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF | JAK1, TNF, CYP4A11 | CXCR1 310/4885CXCR2 288/4885PTGS2 37/4885 |
| US-20070105916-A1 | Amphiphilic pyridinium compounds, method of making and use thereof | CXCL8, IL18, CCR8 | CXCR1 213/4885CXCR2 592/4885PTGS2 544/4885 |
| US-20140378692-A1 | METHOD FOR PRODUCING CARBOXYLIC ACID AND ALCOHOL BY HYDROLYSIS OF ESTER | ADH5, ADH1C, ADH1A | CXCR1 4739/4885CXCR2 4848/4885PTGS2 734/4885 |
| US-12290519-B2 | Anti-inflammatory coupling compound drug, and preparation method therefor and use thereof | JAK1, TNF, CYP4A11 | CXCR1 310/4885CXCR2 288/4885PTGS2 37/4885 |
| US-20250241922-A1 | ANTI-INFLAMMATORY COUPLING COMPOUND DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF | JAK1, TNF, CYP4A11 | CXCR1 310/4885CXCR2 288/4885PTGS2 37/4885 |
| US-20240197741-A1 | EXTERNAL ANTI-INFLAMMATORY COUPLING COMPOUND DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF | TNF, CYP4A11, JAK1 | CXCR1 824/4885CXCR2 691/4885PTGS2 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.