Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 7/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5283300 | 0.88 | CRHR1 (0.37) | MRGPRX4MAPT | |
| SCHEMBL5775424 | 0.86 | EGLN2 (0.41) | EGLN2CYP11B2CYP11B1CYP19A1AR | |
| SCHEMBL4505734 | 0.84 | EGLN2 (0.40) | EGLN2CYP11B2CYP11B1CYP19A1AR | |
| SCHEMBL5771739 | 0.81 | EGLN2 (0.37) | EGLN2CYP11B2CYP11B1CYP19A1AR | |
| SCHEMBL5768799 | 0.81 | EGLN2 (0.37) | EGLN2CYP11B2CYP11B1CYP19A1AR | |
| SCHEMBL4017079 | 0.76 | CRHR1 (0.35) | MRGPRX4 | |
| SCHEMBL5749050 | 0.74 | EGLN2 (0.35) | EGLN2CYP11B2CYP11B1CYP19A1SLC22A12 | |
| SCHEMBL5774051 | 0.74 | EGLN2 (0.35) | EGLN2CYP11B2CYP11B1CYP19A1SLC22A12 | |
| SCHEMBL5291917 | 0.73 | CNR1 (0.37) | MRGPRX4 | |
| SCHEMBL3536164 | 0.72 | DPP4 (0.43) | MEN1KMT2AMRGPRX4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718652-A2 | PYRAZOLOPYRIMIDINES FOR COMBATTING UNWANTED MICROORGANISMS | Bayer CropScience Aktiengesellschaft (DE) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005082907-A2 | PYRAZOLOPYRIMIDINES FOR CONTROLLING UNDESIRED MICROORGANISMS | BAYER CROPSCIENCE AG (DE) | 2005-09-09 | — | — | WO | disclosed |