Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | STK17B | O94768 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399559 | 0.82 | MAPT (0.54) | CKS1BSKP1SKP2MEN1KMT2A | |
| SCHEMBL26313896 | 0.81 | IDO1 (0.45) | CKS1BSKP1SKP2MEN1KMT2A | |
| SCHEMBL26313798 | 0.78 | IDO1 (0.43) | CKS1BSKP1SKP2MEN1KMT2A | |
| SCHEMBL30597303 | 0.78 | IDO1 (0.43) | CKS1BSKP1SKP2MEN1KMT2A | |
| SCHEMBL18918089 | 0.75 | MEN1 (0.50) | CKS1BSKP1SKP2MEN1KMT2A | |
| SCHEMBL1433076 | 0.74 | MAPT (0.49) | CKS1BSKP1SKP2MEN1KMT2A | |
| SCHEMBL8747512 | 0.74 | KMT2A (0.50) | CKS1BSKP1SKP2MEN1KMT2A | |
| SCHEMBL31117833 | 0.74 | CKS1B (0.45) | CKS1BSKP1SKP2MEN1KMT2A | |
| SCHEMBL3722147 | 0.74 | DRD2 (0.46) | CKS1BSKP1SKP2MEN1KMT2A | |
| SCHEMBL11744842 | 0.74 | IDO1 (0.42) | CKS1BSKP1SKP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638944-A1 | TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2006-03-29 | — | — | EP | disclosed |
| WO-2005000821-A1 | TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2005-01-06 | — | — | WO | disclosed |