Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.45 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2186974 | 0.94 | CACNA2D1 (0.48) | NPSR1MEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL2187026 | 0.85 | NPSR1 (0.55) | NPSR1MEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL28764306 | 0.85 | NPSR1 (0.49) | NPSR1MEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL2186561 | 0.81 | NPSR1 (0.49) | NPSR1MEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL2188126 | 0.80 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1LMNAPOLBHTT | |
| SCHEMBL27698639 | 0.80 | KMT2A (0.46) | NPSR1MEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL2186625 | 0.80 | MAPT (0.56) | NPSR1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL27679714 | 0.80 | NPSR1 (0.49) | NPSR1MEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL2192226 | 0.77 | KMT2A (0.55) | NPSR1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2186594 | 0.76 | TNKS (0.49) | NPSR1MEN1KMT2ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1637529-A1 | Novel piperidin-4-yl-thiazole-carboxamide analogues as inhibitors of T-cell proliferation and uses thereof | 4SC AG (DE) | 2006-03-22 | — | — | EP | disclosed |