Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 2/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.49 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.45 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CACNA2D1 | P54289 | 4/20 | 0.42 |
| ▸ | CACNB1 | Q02641 | 4/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2187684 | 0.85 | HSD11B1 (0.48) | TNKSPARP1PARP10TNKS2TRPC3 | |
| SCHEMBL2186835 | 0.82 | TSHR (0.46) | TNKSPARP1PARP10TNKS2TRPC3 | |
| SCHEMBL5769877 | 0.76 | NPSR1 (0.51) | SMN1; SMN2LMNANPSR1ALDH1A1USP2 | |
| SCHEMBL2186561 | 0.75 | NPSR1 (0.49) | SMN1; SMN2LMNANPSR1ALDH1A1USP2 | |
| SCHEMBL2186974 | 0.73 | CACNA2D1 (0.48) | SMN1; SMN2LMNANPSR1ALDH1A1USP2 | |
| SCHEMBL27679714 | 0.71 | NPSR1 (0.49) | SMN1; SMN2LMNANPSR1ALDH1A1USP2 | |
| SCHEMBL2187026 | 0.71 | NPSR1 (0.55) | SMN1; SMN2LMNANPSR1ALDH1A1USP2 | |
| SCHEMBL28764306 | 0.70 | NPSR1 (0.49) | SMN1; SMN2LMNANPSR1ALDH1A1USP2 | |
| SCHEMBL2186866 | 0.68 | NR2E1 (0.47) | SMN1; SMN2LMNANPSR1ALDH1A1USP2 | |
| SCHEMBL766376 | 0.67 | TNKS (0.61) | TNKSPARP1PARP10TNKS2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343293-A1 | NOVEL PIPERIDIN-4-YL-THIAZOLE-CARBOXAMIDE ANALOGUES AS INHIBITORS OF T-CELL PROLIFERATION AND USES THEREOF | 4SC AG (DE) | 2011-07-13 | — | — | EP | disclosed |
| EP-1637529-A1 | Novel piperidin-4-yl-thiazole-carboxamide analogues as inhibitors of T-cell proliferation and uses thereof | 4SC AG (DE) | 2006-03-22 | — | — | EP | disclosed |