Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 12/20 | 0.44 |
| ▸ | CA1 | P00915 | 6/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29163149 | 0.89 | MTNR1A (0.44) | MAPK1GFERCA2CA1CA9 | |
| SCHEMBL3643588 | 0.88 | CA2 (0.48) | CA2CA1CA9CA12GAA | |
| SCHEMBL29163148 | 0.88 | HTR2A (0.43) | MAPK1GFERCA2CA1CA9 | |
| SCHEMBL32664548 | 0.88 | HTR2A (0.43) | MAPK1GFERCA2CA1CA9 | |
| SCHEMBL1804433 | 0.87 | CA2 (0.44) | CA2CA1CA9CA12GAA | |
| SCHEMBL28363919 | 0.86 | CA2 (0.43) | CA2CA1CA9CA12GAA | |
| SCHEMBL12499026 | 0.86 | CA2 (0.43) | CA2CA1CA9CA12GAA | |
| SCHEMBL1804435 | 0.86 | CA1 (0.46) | CA2CA1CA9CA12GAA | |
| SCHEMBL1808208 | 0.83 | CA2 (0.47) | CA2CA1CA9CA12GAA | |
| SCHEMBL1808211 | 0.82 | PTGS2 (0.52) | CA2CA1CA9CA12GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648896-A1 | 7-SUBSTITUTED 3-NITRO-PYRAZOLO [1,5-A] PYRIMIDINES | FERRER INTERNACIONAL, S.A. (ES) | 2006-04-26 | — | — | EP | claimed |
| WO-2005014596-A1 | 7-SUBSTITUTED 3-NITRO-PYRAZOLO `1,5-A! PYRIMIDINES | FERRER INTERNACIONAL, S.A. (ES) | 2005-02-17 | — | — | WO | claimed |