SCHEMBL7941542

SCHEMBL7941542

Cc1ccccc1Nc1ccccn1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK10 P53779 2/20 0.73
MEN1 O00255 2/20 0.73
KMT2A Q03164 2/20 0.73
GFER P55789 2/20 0.73
NPC1 O15118 2/20 0.60
RAB9A P51151 2/20 0.60
NPSR1 Q6W5P4 1/20 0.60
CCNK O75909 1/20 0.60
CCNA2 P20248 1/20 0.60
CDK2 P24941 1/20 0.60
CCND3 P30281 1/20 0.60
CDK9 P50750 1/20 0.60
CDK6 Q00534 1/20 0.60
MAPT P10636 2/20 0.51
ALDH1A1 P00352 2/20 0.51
KDR P35968 1/20 0.50
SLC2A1 P11166 1/20 0.47
ADRA2A P08913 1/20 0.46
ADRA2B P18089 1/20 0.46
ADRA2C P18825 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31220877 1.00 MAPK10 (0.73) MAPK10MEN1KMT2AGFERNPC1
SCHEMBL3279571 0.85 MEN1 (1.00) MAPK10MEN1KMT2AGFERNPC1
SCHEMBL18199830 0.84 MEN1 (0.67) MAPK10MEN1KMT2AGFERNPC1
SCHEMBL5771649 0.82 MAPK10 (0.70) MAPK10MEN1KMT2AGFERNPC1
SCHEMBL5779642 0.82 MAPK10 (0.58) MAPK10MEN1KMT2AGFERNPC1
SCHEMBL3265735 0.80 MEN1 (0.80) MAPK10MEN1KMT2AGFERNPC1
SCHEMBL4391902 0.79 MAPK10 (0.56) MAPK10MEN1KMT2AGFERCCNK
SCHEMBL1518724 0.79 MAPK10 (1.00) MAPK10MEN1KMT2AGFERNPC1
SCHEMBL10094592 0.79 MAPK10 (0.60) MAPK10MEN1KMT2AGFERNPC1
SCHEMBL3950995 0.79 HTT (0.56) MAPK10KMT2AGFERNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10868262-B2 Organometallic complex, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2020-12-15 US disclosed
CN-107973779-B Preparation method of N- (2-pyridine/pyrimidine-based) indole derivative 华侨大学 2020-05-05 CN disclosed
US-20190088890-A1 Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-03-21 US disclosed
EP-1625133-B1 NITROGEN-CONTAINING MONODENTATE PHOSPHINES AND THEIR USE IN CATALYSIS EVONIK DEGUSSA GMBH (DE) 2016-06-29 EP disclosed
US-7589081-B2 Nitrogen-containing monodentate phosphines and their use in catalysis DEGUSSA GMBH (DE) 2009-09-15 US disclosed
US-7589081-B2 Nitrogen-containing monodentate phosphines and their use in catalysis DEGUSSA GMBH (DE) 2009-09-15 US disclosed
US-20070123707-A1 Nitrogen-containing monodentate phosphines and their use in catalysis DEGUSSA AG (DE) 2007-05-31 US disclosed
US-20070123707-A1 Nitrogen-containing monodentate phosphines and their use in catalysis DEGUSSA AG (DE) 2007-05-31 US disclosed
EP-0712278-B1 N-PYRIDYLTOLUIDINE-CONTAINING FUNGICIDAL WATER DISPERSIBLE GRANULES ISHIHARA SANGYO KAISHA (JP) 2001-06-13 EP disclosed
US-6235730-B1 ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT JAPAN TOBACCO, INC. (JP) 2001-05-22 US disclosed
EP-0970954-A1 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME JAPAN TOBACCO INC. (JP) 2000-01-12 EP disclosed
EP-0712278-A1 N-PYRIDYLTOLUIDINE-CONTAINING FUNGICIDAL WATER DISPERSIBLE GRANULES ISHIHARA SANGYO KAISHA, LTD. (JP) 1996-05-22 EP disclosed
EP-0712278-A1 N-PYRIDYLTOLUIDINE-CONTAINING FUNGICIDAL WATER DISPERSIBLE GRANULES ISHIHARA SANGYO KAISHA, LTD. (JP) 1996-05-22 EP disclosed
WO-1995004460-A1 N-PYRIDYLTOLUIDINE-CONTAINING FUNGICIDAL WATER DISPERSIBLE GRANULES ISHIHARA SANGYO KAISHA LTD. (JP) 1995-02-16 WO disclosed
WO-1995004460-A1 N-PYRIDYLTOLUIDINE-CONTAINING FUNGICIDAL WATER DISPERSIBLE GRANULES ISHIHARA SANGYO KAISHA LTD. (JP) 1995-02-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190088890-A1 Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device PPOX, LAGE3, PNPO MAPK10 3228/4885MEN1 2096/4885KMT2A 1596/4885
US-10868262-B2 Organometallic complex, light-emitting element, light-emitting device, electronic device, and lighting device PPOX, LAGE3, PNPO MAPK10 3228/4885MEN1 2096/4885KMT2A 1596/4885
US-20070123707-A1 Nitrogen-containing monodentate phosphines and their use in catalysis HDHD5, PNP, PHOSPHO1 MAPK10 1222/4885MEN1 463/4885KMT2A 2371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.