Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIOK2 | Q9BVS4 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 2/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 3/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.40 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.40 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5778696 | 0.89 | RIOK2 (0.45) | RIOK2MEN1KMT2AMAPK10MAPK9 | |
| SCHEMBL5770717 | 0.87 | RIOK2 (0.44) | RIOK2MEN1KMT2AMAPK10MAPK9 | |
| SCHEMBL5777222 | 0.84 | RIOK2 (0.42) | RIOK2MEN1KMT2AMAPK10MAPK9 | |
| SCHEMBL5771528 | 0.84 | RIOK2 (0.42) | RIOK2MEN1KMT2AMAPK10MAPK9 | |
| SCHEMBL5773999 | 0.84 | RIOK2 (0.42) | RIOK2MEN1KMT2AMAPK10MAPK9 | |
| SCHEMBL5748905 | 0.83 | RIOK2 (0.47) | RIOK2MEN1KMT2AMAPK10MAPK9 | |
| SCHEMBL5749224 | 0.82 | NOS2 (0.50) | RIOK2MEN1KMT2AMAPK10CYP1A2 | |
| SCHEMBL12125849 | 0.81 | RIOK2 (0.51) | RIOK2MEN1KMT2AMAPK10CYP1A2 | |
| SCHEMBL5771191 | 0.81 | MAPK10 (0.51) | RIOK2MEN1KMT2AMAPK10MAPK9 | |
| SCHEMBL5747136 | 0.80 | RIOK2 (0.46) | RIOK2MEN1KMT2AMAPK10MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |