Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CFD | P00746 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.34 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.34 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5772244 | 0.96 | CA12 (0.38) | LMNARECQLCFDCA12CA9 | |
| SCHEMBL5892600 | 0.89 | LMNA (0.47) | LMNARECQLCA12CA9POLB | |
| SCHEMBL5773746 | 0.75 | ALDH1A1 (0.43) | LMNAPOLBHTTHSP90AA1HSP90AB1 | |
| SCHEMBL5771570 | 0.69 | LMNA (0.47) | LMNARECQLCA9POLBPIM1 | |
| SCHEMBL20136021 | 0.69 | CA12 (0.58) | LMNARECQLCA12CA9POLB | |
| SCHEMBL15349582 | 0.69 | LMNA (0.49) | LMNARECQLCA12CA9HTT | |
| SCHEMBL16708129 | 0.67 | MAOB (0.43) | LMNAHTTPIM1MEN1MAPT | |
| SCHEMBL16708178 | 0.67 | PIM1 (0.72) | LMNARECQLPIM1MEN1NPC1 | |
| SCHEMBL27932177 | 0.66 | KDM4E (0.44) | LMNARECQLCFDCA12CA9 | |
| SCHEMBL15623109 | 0.65 | LMNA (0.59) | LMNARECQLCA12CA9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005027900-A1 | BENZOFURAN DERIVATIVES | GALILEO PHARMACEUTICALS, INC. (US) | 2005-03-31 | — | — | WO | disclosed |