Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8253543 | 0.65 | — | — | |
| SCHEMBL762605 | 0.65 | — | — | |
| SCHEMBL17965692 | 0.63 | — | — | |
| SCHEMBL4980791 | 0.62 | — | — | |
| SCHEMBL12052161 | 0.62 | — | — | |
| SCHEMBL13532389 | 0.62 | — | — | |
| SCHEMBL12949434 | 0.61 | — | — | |
| SCHEMBL17528515 | 0.60 | — | — | |
| Ethylene SCHEMBL11844746 | 0.60 | — | — | |
| SCHEMBL337298 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016142952-A1 | PROCESS FOR PREPARATION OF VILAZODONE AND ITS NOVEL INTERMEDIATES | NOSCH LABS PRIVATE LIMITED (IN) | 2016-09-15 | — | — | WO | claimed |
| WO-2025050647-A1 | IONIZABLE CATIONIC LIPID COMPOUNDS AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF | 晟迪生物医药(苏州)有限公司 | 2025-03-13 | — | — | WO | disclosed |
| CN-117986153-A | Ionizable cationic lipid compound, and preparation method and application thereof | 晟迪生物医药(苏州)有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2016142952-A1 | PROCESS FOR PREPARATION OF VILAZODONE AND ITS NOVEL INTERMEDIATES | NOSCH LABS PRIVATE LIMITED (IN) | 2016-09-15 | — | — | WO | disclosed |
| US-9035070-B2 | Process for the preparation of 1-aryl-pyrazol-3-one intermediates useful in the synthesis of sigma receptors inhibitors | Esteve Química, S.A. (ES) | 2015-05-19 | — | — | US | disclosed |
| CN-103038208-B | Process for the preparation of 1-aryl-pyrazol-3-one intermediates useful in the synthesis of sigma receptors inhibitors | ESTEVE QUIMICA SA | 2015-05-06 | — | — | CN | disclosed |
| EP-2598469-B1 | PROCESS FOR THE PREPARATION OF 1-ARYL-PYRAZOL-3-ONE INTERMEDIATES USEFUL IN THE SYNTHESIS OF SIGMA RECEPTORS INHIBITORS | ESTEVE QUÍMICA S A (ES) | 2014-07-23 | — | — | EP | disclosed |
| US-20130184472-A1 | Process for the Preparation of 1-ARYL-PYRAZOL-3-ONE Intermediates Useful in the Synthesis of SIGMA Receptors Inhibitors | ESTEVE QUIMICA, S.A. (ES) | 2013-07-18 | — | — | US | disclosed |
| EP-2418192-A1 | Intermediates for the preparation of 1-aryl-pyrazol-3-one compounds useful as sigma receptors inhibitors | Esteve Química, S.A. (ES) | 2012-02-15 | — | — | EP | disclosed |
| US-20110009596-A1 | PROCESS FOR THE PREPARATION OF N-PROTECTED-DECYLAMINOETHANAL | PLUS CHEMICALS SA (CH) | 2011-01-13 | — | — | US | disclosed |
| WO-2009010296-A2 | ANTIBODIES AGAINST 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE AND METABOLITES THEREOF | CENTRE DE RECHERCHE PUBLIQUE SANTÉ (LU) | 2009-01-22 | — | — | WO | disclosed |
| EP-2016954-A1 | Antibodies against 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and metabolites thereof | Muller, Claude P. (LU) | 2009-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130184472-A1 | Process for the Preparation of 1-ARYL-PYRAZOL-3-ONE Intermediates Useful in the Synthesis of SIGMA Receptors Inhibitors | SIGMAR1, OPRK1, OPRM1 | TSHR 108/4885 |
| US-20110009596-A1 | PROCESS FOR THE PREPARATION OF N-PROTECTED-DECYLAMINOETHANAL | PTMA, DNPEP, TET2 | TSHR 3441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.