Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 14/20 | 0.78 |
| ▸ | PRKCI | P41743 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5773169 | 0.98 | NPY5R (0.74) | NPY5RPRKCIKCNH2SMN1; SMN2MEN1 | |
| SCHEMBL5771155 | 0.88 | NPY5R (0.78) | NPY5RPRKCISMN1; SMN2MEN1KMT2A | |
| SCHEMBL5773316 | 0.88 | NPY5R (1.00) | NPY5RPRKCISMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5773817 | 0.87 | NPY5R (0.76) | NPY5RPRKCISMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5774363 | 0.86 | NPY5R (0.97) | NPY5RPRKCISMN1; SMN2MEN1KMT2A | |
| SCHEMBL22727925 | 0.77 | NPY5R (0.65) | NPY5RPRKCI | |
| SCHEMBL5774720 | 0.73 | NPY5R (1.00) | NPY5R | |
| SCHEMBL5772009 | 0.73 | MEN1 (0.67) | NPY5RSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5772205 | 0.72 | NPY5R (0.69) | NPY5RPRKCIKCNH2SMN1; SMN2 | |
| SCHEMBL5776579 | 0.72 | NPY5R (0.72) | NPY5RPRKCISMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054887-B1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | AMGEN INC (US) | 2006-04-12 | — | — | EP | claimed |