SCHEMBL2965812

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5771832	0.87	TRPA1 (0.34)	POLBDPP4KDM4ENPSR1GAA
	SCHEMBL2960923	0.85	DPP4 (0.45)	POLBHIF1ADPP4ALDH1A1TP53
	SCHEMBL5718898	0.83	LMNA (0.54)	POLBHIF1AALDH1A1KDM4ETP53
	SCHEMBL555650	0.82	HIF1A (0.57)	POLBHIF1ADPP4ALDH1A1KDM4E
	SCHEMBL6384057	0.80	POLB (0.45)	POLBHIF1ADPP4ALDH1A1KDM4E
	SCHEMBL6381665	0.80	P2RX3 (0.35)	DPP4
	SCHEMBL2961214	0.78	POLB (0.64)	POLBHIF1AALDH1A1MAPTMAPK1
	SCHEMBL5772602	0.77	DPP4 (0.44)	POLBHIF1ADPP4ALDH1A1KDM4E
	SCHEMBL13217680	0.77	SIRT1 (0.51)	ALDH1A1KDM4EADORA1ADORA3MEN1
	SCHEMBL6381671	0.76	DPP4 (0.30)	DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.