Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 17/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 10/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5777074 | 0.84 | S1PR1 (0.43) | TBXA2RPTGDR2 | |
| SCHEMBL5777840 | 0.84 | TBXA2R (0.46) | TBXA2RPTGDRPDE2APTGDR2 | |
| SCHEMBL5836706 | 0.83 | — | — | |
| SCHEMBL5778068 | 0.76 | TBXA2R (0.44) | TBXA2RPTGDRPTGER2PDE2APTGDR2 | |
| SCHEMBL5774565 | 0.75 | TBXA2R (0.57) | TBXA2RPTGDRPTGER2PDE2APTGDR2 | |
| SCHEMBL5775903 | 0.75 | TBXA2R (0.57) | TBXA2RPTGDRPTGER2PDE2APTGDR2 | |
| SCHEMBL5776896 | 0.74 | TBXA2R (0.52) | TBXA2RPTGDRPTGER2PDE2APTGDR2 | |
| SCHEMBL5777130 | 0.73 | S1PR1 (0.44) | TBXA2RPTGDRPDE2A | |
| SCHEMBL5776224 | 0.72 | TBXA2R (0.42) | TBXA2RPTGDRPDE2A | |
| SCHEMBL2926749 | 0.72 | TBXA2R (0.54) | TBXA2RPTGDRPTGER2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395590-B1 | DIHYDROPYRROLO¬1,2-A|INDOLE AND TETRAHYDROPYRIDO¬1,2-A|INDOLE DERIVATIVES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | MERCK FROSST CANADA INC (CA) | 2006-09-27 | — | — | EP | disclosed |