Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 9/20 | 0.42 |
| ▸ | PDE2A | O00408 | 3/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 8/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5777734 | 0.85 | S1PR1 (0.43) | TBXA2RS1PR1S1PR4S1PR5 | |
| SCHEMBL5777130 | 0.85 | S1PR1 (0.44) | TBXA2RPDE2APTGDRS1PR1S1PR4 | |
| SCHEMBL5775903 | 0.83 | TBXA2R (0.57) | TBXA2RPDE2APTGDR | |
| SCHEMBL5774565 | 0.83 | TBXA2R (0.57) | TBXA2RPDE2APTGDR | |
| SCHEMBL5778068 | 0.82 | TBXA2R (0.44) | TBXA2RPDE2APTGDRS1PR1S1PR5 | |
| SCHEMBL5774771 | 0.77 | TBXA2R (0.56) | TBXA2RPDE2APTGDR | |
| SCHEMBL5775625 | 0.73 | S1PR1 (0.47) | TBXA2RS1PR1S1PR4S1PR5 | |
| SCHEMBL5772689 | 0.72 | TBXA2R (0.39) | TBXA2RPDE2APTGDR | |
| SCHEMBL5776803 | 0.72 | HTT (0.34) | — | |
| SCHEMBL5777074 | 0.70 | S1PR1 (0.43) | TBXA2RS1PR1S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395590-B1 | DIHYDROPYRROLO¬1,2-A|INDOLE AND TETRAHYDROPYRIDO¬1,2-A|INDOLE DERIVATIVES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | MERCK FROSST CANADA INC (CA) | 2006-09-27 | — | — | EP | disclosed |