Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21662990 | 0.77 | KMT2A (0.39) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL24495521 | 0.76 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL21663006 | 0.76 | STK17B (0.38) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL896209 | 0.75 | MEN1 (0.56) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL21381504 | 0.74 | MAPK1 (0.38) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL16709919 | 0.74 | MAPT (0.67) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL30173602 | 0.74 | MAPT (0.67) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL3968921 | 0.74 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL9948150 | 0.73 | MEN1 (0.54) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL13783520 | 0.73 | MEN1 (0.54) | MEN1KMT2AALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006066899-A1 | NOVEL THROMBIN INHIBITORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2006-06-29 | — | — | WO | disclosed |
| EP-1674464-A1 | Novel thrombin inhibitors | Santhera Pharmaceuticals (Schweiz) GmbH (CH) | 2006-06-28 | — | — | EP | disclosed |
| EP-1674464-A1 | Novel thrombin inhibitors | Santhera Pharmaceuticals (Schweiz) GmbH (CH) | 2006-06-28 | — | — | EP | disclosed |