Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 7/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PIR | O00625 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5772810 | 1.00 | AR (0.52) | ARKMT2ASMN1; SMN2ADAMTS4MMP13 | |
| SCHEMBL5772803 | 1.00 | AR (0.52) | ARKMT2ASMN1; SMN2ADAMTS4MMP13 | |
| SCHEMBL5774170 | 0.81 | BCL2 (0.47) | ARKMT2ASMN1; SMN2ADAMTS4MMP13 | |
| SCHEMBL5774177 | 0.81 | BCL2 (0.47) | ARKMT2ASMN1; SMN2ADAMTS4MMP13 | |
| SCHEMBL292958 | 0.78 | ALDH1A1 (0.53) | KMT2AALDH1A1MAPTCA2CA7 | |
| SCHEMBL472429 | 0.78 | ALDH1A1 (0.53) | KMT2AALDH1A1MAPTCA2CA7 | |
| SCHEMBL258422 | 0.78 | ALDH1A1 (0.53) | KMT2AALDH1A1MAPTCA2CA7 | |
| SCHEMBL130104 | 0.78 | ALDH1A1 (0.53) | KMT2AALDH1A1MAPTCA2CA7 | |
| SCHEMBL10193067 | 0.78 | ALDH1A1 (0.53) | KMT2AALDH1A1MAPTCA2CA7 | |
| SCHEMBL29500256 | 0.78 | ALDH1A1 (0.53) | KMT2AALDH1A1MAPTCA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1676635-A2 | Immobilisable ligands derived from ethylenediamine | Johnson Matthey PLC (GB) | 2006-07-05 | — | — | EP | disclosed |
| US-20060135355-A1 | Nitrogen-containing ligands | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2006-06-22 | — | — | US | disclosed |
| EP-1545772-A2 | NITROGEN-CONTAINING LIGANDS | Johnson Matthey PLC (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004014551-A2 | IMMOBILISED LIGANDS DERIVED FROM ETHYLENEDIAMINE | JOHNSON MATTHEY PLC (GB) | 2004-02-19 | — | — | WO | disclosed |