SCHEMBL258422

SCHEMBL258422

Cc1ccc(S(=O)(=O)N[C@H](c2ccccc2)[C@H](N)c2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.53
NPSR1 Q6W5P4 4/20 0.53
SLC1A3 P43003 1/20 0.51
SLC1A2 P43004 1/20 0.51
SLC1A1 P43005 1/20 0.51
HTT P42858 2/20 0.49
CA12 O43570 3/20 0.49
CA9 Q16790 3/20 0.49
CA2 P00918 2/20 0.49
CA1 P00915 1/20 0.49
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
LMNA P02545 2/20 0.47
MAPT P10636 1/20 0.47
HPN P05981 2/20 0.47
PLAU P00749 1/20 0.47
CA7 P43166 1/20 0.47
CYP1A2 P05177 2/20 0.46
CYP3A4 P08684 2/20 0.46
GAA P10253 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL130104 1.00 ALDH1A1 (0.53) ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1
SCHEMBL1464202 1.00 ALDH1A1 (0.53) ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1
SCHEMBL10193067 1.00 ALDH1A1 (0.53) ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1
SCHEMBL29500256 1.00 ALDH1A1 (0.53) ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1
SCHEMBL472429 1.00 ALDH1A1 (0.53) ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1
SCHEMBL292958 1.00 ALDH1A1 (0.53) ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1
SCHEMBL2239236 1.00 ALDH1A1 (0.53) ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1
SCHEMBL13050357 1.00 ALDH1A1 (0.53) ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1
SCHEMBL7089968 0.98 ALDH1A1 (0.52) ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1
P-Xylene SCHEMBL5424500 0.98 ALDH1A1 (0.52) ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 722 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070891-A1 METHOD FOR PRODUCING QUINOXALINE DERIVATIVE KYOWA KIRIN CO., LTD. (JP) 2026-03-12 US claimed
EP-3818068-B1 NEUROACTIVE STEROIDS AND METHODS OF PREPARATION DRAWBRIDGE PHARMACEUTICALS PTY LTD (AU) 2025-10-29 EP claimed
EP-4582419-A1 METHOD FOR PRODUCING QUINOXALINE DERIVATIVE Kyowa Kirin Co., Ltd. (JP) 2025-07-09 EP claimed
WO-2025074394-A1 A PROCESS FOR THE PREPARATION OF BELZUTIFAN AND ITS NOVEL INTERMEDIATES THEREOF NATCO PHARMA LIMITED (IN) 2025-04-10 WO claimed
WO-2025058704-A1 PROCESS FOR THE PREPARATION OF EPINEPHRINE AND NOREPINEPHRINE VIRGINIA COMMONWEALTH UNIVERSITY (US) 2025-03-20 WO claimed
WO-2025059259-A1 NEW PROCESS FOR PHENYLEPHRINE AND SALBUTAMOL AND RELATED COMPOUNDS VIA ASYMETRIC TRANSFER HYDROGENATION OF UNPROTECTED AMINO KETONES VIRGINIA COMMONWEALTH UNIVERSITY (US) 2025-03-20 WO claimed
WO-2025059054-A1 PROCESS FOR PREPARING (2S,4S,4'S,6S)-2-METHYL-6-(1-METHYL-1H-1,2,3-TRIAZOL-4-YL)-2',-(TRIELUOROMETHYL)-4',5'-DIHYDROSPIRO[PIPERIDINE-4,7'-THIENO [2,3-C] PYRAN] -4'-OL VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-03-20 WO claimed
EP-3694864-B1 BORONIC ACID DERIVATIVES AND SYNTHESIS THEREOF QPEX BIOPHARMA INC (US) 2025-03-05 EP claimed
US-12202820-B2 Pyrimidine derivative and preparation process and use thereof GUANGDONG LEWWIN PHARMACEUTICAL RESEARCH INSTITUTE CO., LTD. (CN) 2025-01-21 US claimed
CN-118344314-A Method for safely preparing gamma-valerolactone by taking formic acid as hydrogen source 南京工业大学 2024-07-16 CN claimed
US-20030225153-A1 Process for preparing arylaminopropanols LANXESS DEUTSCHLAND GMBH (DE) 2003-12-04 US claimed
US-20030225274-A1 Process for reducing 3-heteroaryl-3-oxopropionic acid derivatives LANXESS DEUTSCHLAND GMBH (DE) 2003-12-04 US claimed
EP-1346977-A1 Method for producing aryl-aminopropanols Bayer Aktiengesellschaft (DE) 2003-09-24 EP claimed
EP-1340746-A1 Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives BAYER AG (DE) 2003-09-03 EP claimed
US-20030130521-A1 Substituted acetylpyridine derivatives and process for the preparation of intermediates for optically active beta3 agonist by the use of the same KANEKA CORPORATION (JP) 2003-07-10 US claimed
US-6458962-B1 VIRICIDES FOR TREATMENT OF AIDS AND HYDROGENATION OF COMPOUNDS THE UNIVERSITY OF TENNESSEEE RESEARCH CORPORATION 2002-10-01 US claimed
EP-0915076-B1 Process for the preparation of trans-(R,R)-actinol HOFFMANN LA ROCHE (CH) 2002-01-16 EP claimed
EP-1153919-A1 SUBSTITUTED ACETYLPYRIDINE DERIVATIVES AND PROCESS FOR THE PREPARATION OF INTERMEDIATES FOR OPTICALLY ACTIVE BETA3 AGONIST BY THE USE OF THE SAME KANEKA CORPORATION (JP) 2001-11-14 EP claimed
US-6187961-B1 HYDROGENATING (R)-LEVODIONE IN PRESENCE OF HYDROGEN DONAR AND A SOLVENT OR IN PRESENCE OF HYDROGEN DONOR WHICH SIMULTANEOUSLY USED AS THE SOLVENT, AND AN AMINO-AMIDE-RUTHENIUM COMPLEX ROCHE VITAMINS INC. 2001-02-13 US claimed
EP-0915076-A1 Process for the preparation of trans-(R,R)-actinol F. HOFFMANN-LA ROCHE AG (CH) 1999-05-12 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030130521-A1 Substituted acetylpyridine derivatives and process for the preparation of intermediates for optically active beta3 agonist by the use of the same ADRB3, ADRB2, ADRB1 ALDH1A1 184/4885NPSR1 284/4885SLC1A3 1594/4885
US-20030225153-A1 Process for preparing arylaminopropanols AHR, CYP1A1, CYP1A2 ALDH1A1 233/4885NPSR1 1011/4885SLC1A3 1292/4885
US-12202820-B2 Pyrimidine derivative and preparation process and use thereof MET, HCCS, MTR ALDH1A1 1010/4885NPSR1 3342/4885SLC1A3 2009/4885
US-20030225274-A1 Process for reducing 3-heteroaryl-3-oxopropionic acid derivatives GRHPR, HPD, HAAO ALDH1A1 273/4885NPSR1 2556/4885SLC1A3 752/4885
US-20260070891-A1 METHOD FOR PRODUCING QUINOXALINE DERIVATIVE ME1, PYM1, ME3 ALDH1A1 2714/4885NPSR1 3733/4885SLC1A3 2716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.