SCHEMBL10193067

SCHEMBL10193067

Cc1ccc(S(=O)(=O)NC(c2ccccc2)[C@H](N)c2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.53
NPSR1 Q6W5P4 4/20 0.53
SLC1A3 P43003 1/20 0.51
SLC1A2 P43004 1/20 0.51
SLC1A1 P43005 1/20 0.51
HTT P42858 2/20 0.49
CA12 O43570 3/20 0.49
CA9 Q16790 3/20 0.49
CA2 P00918 2/20 0.49
CA1 P00915 1/20 0.49
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
LMNA P02545 2/20 0.47
MAPT P10636 1/20 0.47
HPN P05981 2/20 0.47
PLAU P00749 1/20 0.47
CA7 P43166 1/20 0.47
CYP1A2 P05177 2/20 0.46
CYP3A4 P08684 2/20 0.46
GAA P10253 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL130104 1.00 ALDH1A1 (0.53) ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1
SCHEMBL1464202 1.00 ALDH1A1 (0.53) ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1
SCHEMBL29500256 1.00 ALDH1A1 (0.53) ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1
SCHEMBL472429 1.00 ALDH1A1 (0.53) ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1
SCHEMBL292958 1.00 ALDH1A1 (0.53) ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1
SCHEMBL258422 1.00 ALDH1A1 (0.53) ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1
SCHEMBL2239236 1.00 ALDH1A1 (0.53) ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1
SCHEMBL13050357 1.00 ALDH1A1 (0.53) ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1
SCHEMBL7089968 0.98 ALDH1A1 (0.52) ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1
P-Xylene SCHEMBL5424500 0.98 ALDH1A1 (0.52) ALDH1A1NPSR1SLC1A3SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3106453-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND, AND NOVEL METAL-DIAMINE COMPLEX Takasago International Corporation (JP) 2016-12-21 EP disclosed
EP-2609103-B1 RUTHENIUM-DIAMINE COMPLEXES AND METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUNDS TAKASAGO PERFUMERY CO LTD (JP) 2015-08-19 EP disclosed
EP-2703386-A1 METHOD FOR PRODUCING DIAMINE COMPOUND Takasago International Corporation (JP) 2014-03-05 EP disclosed
WO-2012026201-A1 RUTHENIUM-DIAMINE COMPLEXES AND METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUNDS TAKASAGO INTERNATIONAL CORPORATION (JP) 2012-03-01 WO disclosed