Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10013281 | 1.00 | KMT2A (0.58) | KMT2AMAPK1GRM5HSD11B1HSD17B2 | |
| SCHEMBL14139680 | 0.86 | KMT2A (0.54) | KMT2AMAPK1GRM5HSD11B1HSD17B2 | |
| SCHEMBL576462 | 0.83 | KMT2A (0.63) | KMT2AMAPK1GRM5HSD11B1HSD17B2 | |
| SCHEMBL523899 | 0.83 | KMT2A (0.63) | KMT2AMAPK1GRM5HSD11B1HSD17B2 | |
| SCHEMBL523900 | 0.83 | KMT2A (0.63) | KMT2AMAPK1GRM5HSD11B1HSD17B2 | |
| SCHEMBL576463 | 0.83 | KMT2A (0.63) | KMT2AMAPK1GRM5HSD11B1HSD17B2 | |
| SCHEMBL4529849 | 0.83 | KMT2A (0.63) | KMT2AMAPK1GRM5HSD11B1HSD17B2 | |
| SCHEMBL5626616 | 0.83 | KMT2A (0.63) | KMT2AMAPK1GRM5HSD11B1HSD17B2 | |
| SCHEMBL27902911 | 0.83 | KMT2A (0.63) | KMT2AMAPK1GRM5HSD11B1HSD17B2 | |
| SCHEMBL8207326 | 0.83 | KMT2A (0.63) | KMT2AMAPK1GRM5HSD11B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8212072-B2 | Process for the preparation of pregabalin | Divi's Laboratories, Ltd. (IN) | 2012-07-03 | — | — | US | claimed |
| US-20120041212-A1 | PROCESS FOR THE PREPARATION OF PREGABALIN | DIVI'S LABORATORIES LIMITED (IN) | 2012-02-16 | — | — | US | claimed |
| EP-2418194-A1 | Process for the preparation of pregabalin | Divi's Laboratories Limited (IN) | 2012-02-15 | — | — | EP | claimed |
| US-8212072-B2 | Process for the preparation of pregabalin | Divi's Laboratories, Ltd. (IN) | 2012-07-03 | — | — | US | disclosed |
| US-20120041212-A1 | PROCESS FOR THE PREPARATION OF PREGABALIN | DIVI'S LABORATORIES LIMITED (IN) | 2012-02-16 | — | — | US | disclosed |
| EP-2418194-A1 | Process for the preparation of pregabalin | Divi's Laboratories Limited (IN) | 2012-02-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041212-A1 | PROCESS FOR THE PREPARATION OF PREGABALIN | GABRA5, GABRA6, GABRE | KMT2A 2233/4885MAPK1 3216/4885GRM5 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.