Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15953915 | 0.98 | MEN1 (0.52) | MEN1KMT2ACDK2CYP1A2CYP2C9 | |
| SCHEMBL929085 | 0.92 | MAPT (0.50) | MEN1KMT2ACDK2CYP1A2CYP2C9 | |
| SCHEMBL12124647 | 0.86 | MAPT (0.45) | MEN1KMT2ACDK2CYP1A2CYP2C9 | |
| SCHEMBL27547587 | 0.86 | MAPT (0.47) | MEN1KMT2ACDK2CYP1A2CYP2C9 | |
| SCHEMBL15223292 | 0.86 | MAPT (0.47) | MEN1KMT2ACDK2CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL15204558 | 0.85 | MAPT (0.44) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL4714497 | 0.85 | MAPT (0.46) | MEN1KMT2ACDK2CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL4714494 | 0.85 | MAPT (0.46) | MEN1KMT2ACDK2CYP1A2CYP2C9 | |
| SCHEMBL16444047 | 0.82 | ALDH1A1 (0.50) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL16444049 | 0.82 | ALDH1A1 (0.50) | MEN1KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7098220-B2 | Imidazopyridine derivatives, preparation method and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2006-08-29 | — | — | US | disclosed |
| EP-1558612-B1 | IMIDAZOPYRIDINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2006-08-23 | — | — | EP | disclosed |
| US-20060069117-A1 | Imidazopyridine derivatives, preparation method and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2006-03-30 | — | — | US | disclosed |
| EP-1558612-A1 | IMIDAZOPYRIDINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004043957-A1 | IMIDAZOPYRIDINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2004-05-27 | — | — | WO | disclosed |
| US-4144341-A | ANTIPYRETICS, ANALGESICS AND ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. (US) | 1979-03-13 | — | — | US | disclosed |
| US-4000286-A | ANALGESICS, ANTIINFLAMMATORY AND ANTIPYRETIC AGENTS | MERCK & CO., INC. (US) | 1976-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069117-A1 | Imidazopyridine derivatives, preparation method and pharmaceutical compositions containing same | PRKAA1, PRKAB1, PRKAB2 | MEN1 3065/4885KMT2A 1946/4885CDK2 1694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.