Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.46 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.46 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952327 | 0.85 | ERN1 (0.62) | ERN1LMNAHTTKMT2AMEN1 | |
| SCHEMBL2652355 | 0.82 | ERN1 (0.69) | ERN1LMNAHTTKMT2APTPN1 | |
| SCHEMBL203753 | 0.78 | ERN1 (0.59) | ERN1LMNAHTTKMT2AMEN1 | |
| SCHEMBL3030993 | 0.77 | LMNA (0.56) | LMNAHTTKMT2AMEN1TXNRD1 | |
| SCHEMBL6173137 | 0.77 | ERN1 (0.58) | ERN1LMNAHTTPTPN1TXNRD1 | |
| SCHEMBL2616938 | 0.77 | ERN1 (0.58) | ERN1HTTKMT2AMEN1PTPN1 | |
| SCHEMBL1591294 | 0.77 | ERN1 (0.58) | ERN1LMNAHTTKMT2AMEN1 | |
| SCHEMBL1858387 | 0.77 | ALDH1A1 (0.62) | ERN1LMNAHTTKMT2AMEN1 | |
| SCHEMBL918368 | 0.77 | ERN1 (0.73) | ERN1PTPN1TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL1195413 | 0.77 | HSD17B10 (0.62) | ERN1KMT2AMEN1PTPN1TXNRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1112548-A | Polyiodinated compounds, process for preparing them and diagnostic compositions | GUERBET SA (FR) | 1995-11-29 | — | — | CN | claimed |
| CN-115806568-A | Method for constructing heteroatom substituted xanthene derivative through palladium-catalyzed cross coupling and application | 华东师范大学 | 2023-03-17 | — | — | CN | disclosed |
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
| CN-1112548-A | Polyiodinated compounds, process for preparing them and diagnostic compositions | GUERBET SA (FR) | 1995-11-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | ERN1 1816/4885LMNA 861/4885HTT 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.