Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 10/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5771920 | 0.88 | NPY5R (0.42) | NPY5RKDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL5773550 | 0.87 | NPY5R (0.42) | NPY5RKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5769714 | 0.86 | NPY5R (0.53) | NPY5RKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5773813 | 0.85 | NPY5R (0.58) | NPY5RKDM4EALDH1A1HPGDMAPK1 | |
| Hydrochloric Acid SCHEMBL5775998 | 0.83 | NPY5R (0.56) | NPY5RKDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL5771896 | 0.80 | NPY5R (0.52) | NPY5RKDM4EHSD17B10KMT2A | |
| SCHEMBL5773349 | 0.80 | NPY5R (0.52) | NPY5RKDM4EHSD17B10KMT2A | |
| SCHEMBL5776510 | 0.80 | NPY5R (0.44) | NPY5RKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5773681 | 0.79 | NPY5R (0.54) | NPY5RKDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL8129938 | 0.79 | NPY5R (0.56) | NPY5RKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054887-B1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | AMGEN INC (US) | 2006-04-12 | — | — | EP | claimed |