Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6404843 | 0.81 | NR1H2 (0.32) | — | |
| SCHEMBL3533193 | 0.73 | NR3C2 (0.43) | — | |
| SCHEMBL5776726 | 0.73 | TSHR (0.38) | SIRT1 | |
| SCHEMBL5778087 | 0.66 | HSD11B1 (0.39) | — | |
| SCHEMBL3536598 | 0.66 | NR3C1 (0.39) | — | |
| SCHEMBL3532068 | 0.64 | NR3C2 (0.49) | — | |
| SCHEMBL3537462 | 0.64 | KMT2A (0.44) | — | |
| SCHEMBL5926004 | 0.64 | HSD11B1 (0.40) | — | |
| SCHEMBL5779323 | 0.63 | AOC2 (0.40) | — | |
| SCHEMBL6404388 | 0.62 | NR3C1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638945-A1 | HETEROCYCLICALLY SUBSTITUTED PENTANOL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | Schering Aktiengesellschaft (DE) | 2006-03-29 | — | — | EP | disclosed |
| WO-2005003098-A1 | HETEROCYCLICALLY SUBSTITUTED PENTANOL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-01-13 | — | — | WO | disclosed |