SCHEMBL577423

SCHEMBL577423

OCCOCCOc1ccccc1-c1cccc2c1-c1ccccc1C2

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.41
KDM4E B2RXH2 8/20 0.41
KMT2A Q03164 5/20 0.41
MEN1 O00255 4/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
MAPT P10636 1/20 0.41
MAPK1 P28482 1/20 0.41
ADRB2 P07550 1/20 0.41
ADRB1 P08588 1/20 0.41
LMNA P02545 3/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 2/20 0.38
POLB P06746 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PTK2B Q14289 1/20 0.37
USP2 O75604 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28856359 0.83 LMNA (0.44) ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2
SCHEMBL30110485 0.83 LMNA (0.44) ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2
SCHEMBL31388247 0.81 LMNA (0.39) ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2
SCHEMBL29441926 0.79 ALOX5AP (0.49) ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2
SCHEMBL28959455 0.77 ALDH1A1 (0.44) ALDH1A1KDM4EKMT2AMEN1MAPT
SCHEMBL30161609 0.77 ALDH1A1 (0.44) ALDH1A1KDM4EKMT2AMEN1MAPT
SCHEMBL28523963 0.76 KCNA3 (0.45) ALDH1A1KDM4EKMT2AMEN1MAPT
SCHEMBL28479536 0.76 ALDH1A1 (0.46) ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2
SCHEMBL29264510 0.76 THRB (0.49) ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2
SCHEMBL21380737 0.76 LMNA (0.47) ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2418253-A1 POLYCARBONATE RESIN COMPOSITION, PROCESS FOR PRODUCING MOLDED ARTICLE THEREFROM, AND OPTICAL LENS Mitsubishi Gas Chemical Company, Inc. (JP) 2012-02-15 EP disclosed