SCHEMBL577442

SCHEMBL577442

C1=C(SC2=CCCCC2)CCCC1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.34
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
JAK2 O60674 1/20 0.32
JAK1 P23458 1/20 0.32
JAK3 P52333 1/20 0.32
TYMP P19971 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PSMB5 P28074 2/20 0.30
PSMB1 P20618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27913928 0.91 P2RX7 (0.33) HDAC4HDAC2HDAC8HDAC6
SCHEMBL11739526 0.82 KDM1A (0.34) KDM1AHDAC4HDAC2HDAC8HDAC6
SCHEMBL5682496 0.79 FFAR2 (0.41) ALDH1A1TDP1
SCHEMBL27983506 0.78
SCHEMBL21477703 0.78
SCHEMBL1145547 0.78
SCHEMBL29767080 0.78 KDM1A (0.32) KDM1AHDAC4HDAC2HDAC8HDAC6
SCHEMBL1145543 0.78
SCHEMBL1146024 0.76 KDM1A (0.31) KDM1AHDAC4HDAC2HDAC8HDAC6
SCHEMBL1146026 0.76 KDM1A (0.31) KDM1AHDAC4HDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344301-A Tetra-substituted cyclohexene thioether compound, preparation method and application thereof 沈阳万菱生物技术有限公司 2024-07-16 CN disclosed
CN-118344301-A Tetra-substituted cyclohexene thioether compound, preparation method and application thereof 沈阳万菱生物技术有限公司 2024-07-16 CN disclosed
EP-3848399-B1 TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER IDEMITSU KOSAN CO (JP) 2024-07-10 EP disclosed
US-11795188-B2 Transition metal compound and method for producing olefin polymer IDEMITSU KOSAN CO., LTD. (JP) 2023-10-24 US disclosed
US-11718600-B2 1,2,3-triazole inhibitors of P97 AAA ATPase activity University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2023-08-08 US disclosed
US-20230235202-A1 PLASTICIZER FOR RESINS IDEMITSU KOSAN CO.,LTD. (JP) 2023-07-27 US disclosed
EP-3848399-A1 TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER Idemitsu Kosan Co., Ltd. (JP) 2021-07-14 EP disclosed
US-20210198300-A1 TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER IDEMITSU KOSAN CO.,LTD. (JP) 2021-07-01 US disclosed
EP-2915858-B1 ADHESIVE COMPOSITION AND ADHESIVE TAPE USING SAME IDEMITSU KOSAN CO (JP) 2020-12-02 EP disclosed
EP-3006535-B1 BASE POLYMER FOR HOT-MELT ADHESIVE, AND HOT-MELT ADHESIVE IDEMITSU KOSAN CO (JP) 2020-02-05 EP disclosed
US-6730626-B2 TRANSITION METAL DERIVATIVE CAN REACT TO FORM AN IONIC COMPLEX WITH THE ALUMINOXANE IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-05-04 US disclosed
EP-1323723-A1 TRANSITION METAL COMPOUNDS, POLYMERIZATION CATALYSTS FOR OLEFINS, OLEFIN POLYMERS AND PROCESS FOR THEIR PRODUCTION IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-07-02 EP disclosed
US-20020193536-A1 Transition metal compound, polymerization catalysts for olefins, olefin polymers and process for their production IDEMITSU KOSAN CO. LTD. (JP) 2002-12-19 US disclosed
CN-1384849-A Polypropylene film and laminate made therefrom IDEMITSU PETROCHEMICAL CO (JP) 2002-12-11 CN disclosed
CN-1384848-A Polypropylene film and multilayer laminate IDEMITSU PETROCHEMICAL CO (JP) 2002-12-11 CN disclosed
EP-1241206-A1 POLYPROPYLENE FILM AND MULTILAYERED LAMINATE IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-09-18 EP disclosed
EP-1231226-A1 ROLLED POLYPROPYLENE AND INJECTION-MOLDED POLYPROPYLENE IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-08-14 EP disclosed
EP-1231236-A1 POLYPROPYLENE FILM AND MULTILAYERED LAMINATE IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-08-14 EP disclosed
EP-1227112-A1 PROPYLENE POLYMERS AND RESIN COMPOSITION AND MOLDING CONTAINING THE POLYMERS IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-07-31 EP disclosed
EP-1095951-A1 PROPYLENE POLYMER AND COMPOSITION CONTAINING THE SAME, MOLDED OBJECT AND LAMINATE COMPRISING THESE, AND PROCESSES FOR PRODUCING PROPYLENE POLYMER AND COMPOSITION CONTAINING THE SAME IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11718600-B2 1,2,3-triazole inhibitors of P97 AAA ATPase activity ATAD3B, ATAD3A, PSMG3 KDM1A 2541/4885ALDH1A1 2536/4885CYP3A4 3340/4885
US-20210198300-A1 TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER H1-0, C9, C5 KDM1A 1619/4885ALDH1A1 3156/4885CYP3A4 3580/4885
US-20020193536-A1 Transition metal compound, polymerization catalysts for olefins, olefin polymers and process for their production CCNE2, PYM1, AP1M1 KDM1A 943/4885ALDH1A1 2755/4885CYP3A4 765/4885
US-11795188-B2 Transition metal compound and method for producing olefin polymer H1-0, C9, C5 KDM1A 1619/4885ALDH1A1 3156/4885CYP3A4 3580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.