SCHEMBL5774443

SCHEMBL5774443

C=C[Si](C=C)(C=C)c1ccccc1[Si](C=C)(C=C)C=C

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
TSHR P16473 1/20 0.36
HDAC8 Q9BY41 1/20 0.32
GPR3 P46089 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29214166 0.82 NFE2L2 (0.37)
SCHEMBL29214141 0.77 ALDH1A1 (0.35) ALDH1A1
SCHEMBL1674781 0.73 ALDH1A1 (0.41) ALDH1A1TSHRHDAC8
SCHEMBL5774858 0.71 HDAC8 (0.34) ALDH1A1TSHRHDAC8
SCHEMBL3094174 0.71 NR1H2 (0.36) ALDH1A1TSHRHDAC8
SCHEMBL10886349 0.71 TSHR (0.33) ALDH1A1TSHRHDAC8
SCHEMBL5774391 0.67 NR1H2 (0.32) ALDH1A1
SCHEMBL6114057 0.66 HDAC8 (0.31) HDAC8
SCHEMBL29214164 0.66 NFE2L2 (0.37) ALDH1A1
SCHEMBL21143008 0.65 CYP2A6 (0.40) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060134336-A1 Novel polycarbosilane and method of producing the same, film-forming composition, and film and method of forming the same JSR CORPORATION (JP) 2006-06-22 US disclosed
EP-1661934-A1 Polycarbosilane and method of producing the same, film-forming composition, and film and method of forming the same JSR Corporation (JP) 2006-05-31 EP disclosed