SCHEMBL3094174

SCHEMBL3094174

C=C[Si](C)(C)c1ccccc1[Si](C)(C)C=C

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.36
NR1H3 Q13133 1/20 0.36
HDAC8 Q9BY41 1/20 0.34
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9634722 0.85 TSHR (0.39) NR1H2NR1H3HDAC8ALDH1A1TSHR
SCHEMBL2558125 0.84 ALDH1A1 (0.38) NR1H2NR1H3ALDH1A1TSHR
SCHEMBL9179552 0.84 ALDH1A1 (0.36) NR1H2NR1H3ALDH1A1TSHR
SCHEMBL11358166 0.84 ALDH1A1 (0.41) NR1H2NR1H3ALDH1A1TSHR
SCHEMBL21143008 0.80 CYP2A6 (0.40) ALDH1A1TSHR
SCHEMBL7634333 0.80 LMNA (0.46) ALDH1A1TSHR
SCHEMBL7634328 0.79
SCHEMBL2007121 0.79 APOBEC3G (0.41) NR1H2NR1H3
SCHEMBL5774858 0.78 HDAC8 (0.34) HDAC8ALDH1A1TSHR
Phenol SCHEMBL16906342 0.77 CA12 (0.41) NR1H2NR1H3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9403925-B2 Curable composition and cured article ADEKA CORPORATION (JP) 2016-08-02 US claimed
US-7601274-B2 addition-condensation copolymer is formed from hydrosilylation, comprising a liquid crystalline diene, crosslinking agent tetrakis(vinyldimethylsiloxy)silane and hydride-terminated polydimethylsiloxane; implantable medical device, intraocular lens, contact lens; reversible shape changes THE UNIVERSITY OF CONNECTICUT (US) 2009-10-13 US claimed
WO-2005103201-A1 SHAPE MEMORY MAIN-CHAIN SMECTIC-C ELASTOMERS UNIVERSITY OF CONNECTICUT (US) 2005-11-03 WO claimed
US-20050242325-A1 Shape memory main-chain smectic-C elastomers CONNECTICUT, UNIVERSITY OF 2005-11-03 US claimed
EP-3732211-B1 CAPPED DUAL-HEADED ORGANOALUMINUM COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-05-22 EP disclosed
US-11613600-B2 Capped dual-headed organoaluminum compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2023-03-28 US disclosed
EP-3732211-A1 CAPPED DUAL-HEADED ORGANOALUMINUM COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2020-11-04 EP disclosed
US-20200332045-A1 CAPPED DUAL-HEADED ORGANOALUMINUM COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC 2020-10-22 US disclosed
CN-110023270-A Preparation and method for 3D printing ceramic matrix composites HRL实验室有限责任公司 2019-07-16 CN disclosed
CN-110023378-A Monomer preparation and method for 3D printing preceramic polymer HRL实验室有限责任公司 2019-07-16 CN disclosed
CN-109996773-A The method of the preparation and 3D printing of the active functional additive preparation for 3D printing preceramic polymer HRL实验室有限责任公司 2019-07-09 CN disclosed
CN-109715707-A Bridged silicone resins, films, electronic devices, and related methods 美国陶氏有机硅公司 2019-05-03 CN disclosed
US-20090240075-A1 SHAPE MEMORY MAIN-CHAIN SMECTIC-C ELASTOMERS MATHER PATRICK T 2009-09-24 US disclosed
US-20060134336-A1 Novel polycarbosilane and method of producing the same, film-forming composition, and film and method of forming the same JSR CORPORATION (JP) 2006-06-22 US disclosed
EP-1661934-A1 Polycarbosilane and method of producing the same, film-forming composition, and film and method of forming the same JSR Corporation (JP) 2006-05-31 EP disclosed
WO-2005103201-A1 SHAPE MEMORY MAIN-CHAIN SMECTIC-C ELASTOMERS UNIVERSITY OF CONNECTICUT (US) 2005-11-03 WO disclosed
US-20050242325-A1 Shape memory main-chain smectic-C elastomers CONNECTICUT, UNIVERSITY OF 2005-11-03 US disclosed
US-4816496-A HEAT AND LIGHT RESISTANT ADHESIVES AND FILMS KABUSHIKI KAISHA TOSHIBA (JP) 1989-03-28 US disclosed
EP-0282634-A1 Photocurable composition KABUSHIKI KAISHA TOSHIBA (JP) 1988-09-21 EP disclosed
EP-0172330-A1 Photocurable composition KABUSHIKI KAISHA TOSHIBA (JP) 1986-02-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090240075-A1 SHAPE MEMORY MAIN-CHAIN SMECTIC-C ELASTOMERS HBS1L, SMCHD1, SMC2 NR1H2 1035/4885NR1H3 796/4885HDAC8 1997/4885
US-20200332045-A1 CAPPED DUAL-HEADED ORGANOALUMINUM COMPOSITIONS CAPG, C5, CDS2 NR1H2 3805/4885NR1H3 3399/4885HDAC8 4167/4885
US-11613600-B2 Capped dual-headed organoaluminum compositions CAPG, C5, CDS2 NR1H2 3805/4885NR1H3 3399/4885HDAC8 4167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.