Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 12/20 | 0.46 |
| ▸ | PGR | P06401 | 7/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DHPS | P49366 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797178 | 0.93 | NR3C1 (0.51) | NR3C1PGRNR3C2TRPV1 | |
| SCHEMBL5779425 | 0.87 | NR3C1 (0.43) | NR3C1PGRTRPV1DHPS | |
| SCHEMBL6403409 | 0.84 | NR3C1 (0.50) | NR3C1PGRNR3C2TRPV1NPC1 | |
| SCHEMBL5774468 | 0.84 | TRPV1 (0.33) | NR3C1PGRNR3C2TRPV1NPC1 | |
| SCHEMBL5779746 | 0.83 | NR3C1 (0.41) | NR3C1PGRNR3C2TRPV1DHPS | |
| SCHEMBL6408601 | 0.82 | NR3C1 (0.53) | NR3C1PGRNR3C2TRPV1NPC1 | |
| SCHEMBL5778544 | 0.81 | NR3C1 (0.68) | NR3C1PGRNR3C2 | |
| SCHEMBL4732633 | 0.80 | NR3C1 (0.57) | NR3C1PGRNR3C2TRPV1NPC1 | |
| SCHEMBL6405053 | 0.80 | NR3C1 (0.55) | NR3C1PGRNR3C2 | |
| SCHEMBL5780477 | 0.79 | NR3C1 (0.60) | NR3C1PGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638945-A1 | HETEROCYCLICALLY SUBSTITUTED PENTANOL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | Schering Aktiengesellschaft (DE) | 2006-03-29 | — | — | EP | disclosed |
| WO-2005003098-A1 | HETEROCYCLICALLY SUBSTITUTED PENTANOL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-01-13 | — | — | WO | disclosed |