Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 13/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 3/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.32 |
| ▸ | DHPS | P49366 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5779427 | 0.87 | TRPV1 (0.35) | TRPV1DHPS | |
| SCHEMBL5779751 | 0.84 | TRPV1 (0.34) | TRPV1DHPS | |
| SCHEMBL5774465 | 0.84 | NR3C1 (0.46) | TRPV1NR3C1NPC1LMNACYP1A2 | |
| SCHEMBL5797178 | 0.78 | NR3C1 (0.51) | TRPV1NR3C1PGRNR3C2 | |
| SCHEMBL5776235 | 0.71 | NR3C1 (0.42) | NR3C1PGRNR3C2 | |
| SCHEMBL5779425 | 0.71 | NR3C1 (0.43) | TRPV1NR3C1PGRDHPS | |
| SCHEMBL6403409 | 0.70 | NR3C1 (0.50) | TRPV1NR3C1NPC1LMNACYP1A2 | |
| SCHEMBL5779746 | 0.68 | NR3C1 (0.41) | TRPV1NR3C1PGRNR3C2DHPS | |
| SCHEMBL6408601 | 0.67 | NR3C1 (0.53) | TRPV1NR3C1NPC1LMNACYP1A2 | |
| SCHEMBL3533916 | 0.66 | AXL (0.37) | NR3C1PGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638945-A1 | HETEROCYCLICALLY SUBSTITUTED PENTANOL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | Schering Aktiengesellschaft (DE) | 2006-03-29 | — | — | EP | disclosed |
| WO-2005003098-A1 | HETEROCYCLICALLY SUBSTITUTED PENTANOL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-01-13 | — | — | WO | disclosed |