Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.41 |
| ▸ | PGR | P06401 | 3/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.35 |
| ▸ | DHPS | P49366 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5774962 | 0.93 | NR3C1 (0.46) | NR3C1PGRTRPV1NR3C2METTL3 | |
| SCHEMBL5779425 | 0.92 | NR3C1 (0.43) | NR3C1PGRTRPV1METTL3DHPS | |
| SCHEMBL5798295 | 0.84 | NR3C1 (0.48) | NR3C1PGRTRPV1NR3C2METTL3 | |
| SCHEMBL5774465 | 0.83 | NR3C1 (0.46) | NR3C1PGRTRPV1NR3C2DHPS | |
| SCHEMBL5779751 | 0.82 | TRPV1 (0.34) | TRPV1METTL3DHPSRAF1BRAF | |
| SCHEMBL6411423 | 0.82 | NR3C1 (0.46) | NR3C1PGRTRPV1DHPSRAF1 | |
| SCHEMBL4630288 | 0.80 | NR3C1 (0.49) | NR3C1PGRTRPV1NR3C2RAF1 | |
| SCHEMBL5777174 | 0.80 | NR3C1 (0.45) | NR3C1PGRTRPV1NR3C2DHPS | |
| SCHEMBL6404831 | 0.79 | NR3C1 (0.52) | NR3C1PGRTRPV1NR3C2RAF1 | |
| SCHEMBL6405434 | 0.79 | NR3C1 (0.52) | NR3C1PGRTRPV1DHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638945-A1 | HETEROCYCLICALLY SUBSTITUTED PENTANOL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | Schering Aktiengesellschaft (DE) | 2006-03-29 | — | — | EP | disclosed |
| WO-2005003098-A1 | HETEROCYCLICALLY SUBSTITUTED PENTANOL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-01-13 | — | — | WO | disclosed |