Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.60 |
| ▸ | CES1 | P23141 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.48 |
| ▸ | CHRNG | P07510 | 1/20 | 0.48 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | CHRND | Q07001 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23174036 | 0.91 | CES2 (0.67) | CES2CES1LMNAPARP1ALDH1A1 | |
| SCHEMBL10848105 | 0.81 | PARP1 (0.59) | PARP1ALDH1A1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL14114778 | 0.81 | CES2 (0.44) | CES2CES1LMNAPARP1ALDH1A1 | |
| SCHEMBL1794536 | 0.81 | PARP1 (0.50) | CES2CES1PARP1ALDH1A1CHRNA1 | |
| SCHEMBL11754647 | 0.81 | PARP1 (0.50) | CES2CES1PARP1ALDH1A1CHRNA1 | |
| SCHEMBL10497166 | 0.80 | ALDH1A1 (0.60) | CES2CES1LMNAPARP1ALDH1A1 | |
| SCHEMBL10497179 | 0.80 | ALDH1A1 (0.68) | CES2CES1LMNAALDH1A1NPC1 | |
| SCHEMBL742997 | 0.79 | LMNA (0.59) | LMNAPARP1ALDH1A1GLS | |
| SCHEMBL31038341 | 0.79 | LMNA (0.59) | LMNAPARP1ALDH1A1GLS | |
| SCHEMBL742998 | 0.79 | LMNA (0.59) | LMNAPARP1ALDH1A1GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1676635-A2 | Immobilisable ligands derived from ethylenediamine | Johnson Matthey PLC (GB) | 2006-07-05 | — | — | EP | disclosed |
| US-20060135355-A1 | Nitrogen-containing ligands | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2006-06-22 | — | — | US | disclosed |
| EP-1545772-A2 | NITROGEN-CONTAINING LIGANDS | Johnson Matthey PLC (GB) | 2005-06-29 | — | — | EP | disclosed |
| EP-1170279-B1 | Polyphenylene oligomers and polymers | DOW GLOBAL TECHNOLOGIES INC (US) | 2004-09-29 | — | — | EP | disclosed |
| WO-2004014551-A2 | IMMOBILISED LIGANDS DERIVED FROM ETHYLENEDIAMINE | JOHNSON MATTHEY PLC (GB) | 2004-02-19 | — | — | WO | disclosed |
| EP-0889920-B1 | POLYPHENYLENE OLIGOMERS AND POLYMERS | DOW CHEMICAL CO (US) | 2002-02-13 | — | — | EP | disclosed |
| EP-1170279-A1 | Polyphenylene oligomers and polymers | THE DOW CHEMICAL COMPANY (US) | 2002-01-09 | — | — | EP | disclosed |
| US-6288188-B1 | ACETYLENIC POLYMERS; INTEGRATED CIRCUITS, DIELECTRICS, MICROELECTRONICS | THE DOW CHEMICAL COMPANY | 2001-09-11 | — | — | US | disclosed |
| US-5965679-A | BASED A BISCYCLOPENTADIENONE AND AN AROMATIC DIACETYLENE; CURING; LOW DIELECTRIC; INTEGRATED CIRCUITS; MICROELECTRONICS; PRINTED CIRCUITS | THE DOW CHEMICAL COMPANY (US) | 1999-10-12 | — | — | US | disclosed |
| EP-0889920-A1 | POLYPHENYLENE OLIGOMERS AND POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1999-01-13 | — | — | EP | disclosed |
| WO-1998011149-A1 | POLYPHENYLENE OLIGOMERS AND POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1998-03-19 | — | — | WO | disclosed |
| US-4263311-A | ANTIARTHRITIC AGENTS | SMITHKLINE CORPORATION (US) | 1981-04-21 | — | — | US | disclosed |
| US-4190602-A | PHOTOCHEMICAL SENSITIZERS BY REACTION OF SULFUROUS ACID ESTER OR THIONYL CHLORIDE AND A PRIMARY ALCOHOL | CIBA-GEIGY CORPORATION (US) | 1980-02-26 | — | — | US | disclosed |