Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 7/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.43 |
| ▸ | GUSB | P08236 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | PPOX | P50336 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8190255 | 0.78 | ALDH1A1 (0.44) | KDM4ETNFNOD1GUSBALDH1A1 | |
| SCHEMBL5773748 | 0.75 | KDM4E (0.61) | KDM4EGUSBALDH1A1MAPTHSD11B1 | |
| SCHEMBL17351216 | 0.73 | TNF (0.42) | KDM4ETNFNOD1GUSBALDH1A1 | |
| SCHEMBL3565865 | 0.73 | TNF (0.57) | KDM4ETNFNOD1GUSBALDH1A1 | |
| SCHEMBL11252204 | 0.70 | DGAT1 (0.47) | TNFNOD1GUSBALDH1A1HSD11B1 | |
| SCHEMBL29624840 | 0.70 | AHR (0.64) | KDM4EALDH1A1MAPTHSD11B1AHR | |
| SCHEMBL464507 | 0.70 | AHR (0.64) | KDM4EALDH1A1MAPTHSD11B1AHR | |
| SCHEMBL8186413 | 0.68 | ALDH1A1 (0.38) | HSD17B2TNFNOD1HSD17B1ALDH1A1 | |
| SCHEMBL6049622 | 0.67 | TYMS (0.44) | KDM4EGUSBALDH1A1MAPTMEN1 | |
| SCHEMBL8178007 | 0.66 | CNR1 (0.40) | TNFNOD1GUSBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885885-B1 | PYRIDONE DERIVATIVES AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2006-01-04 | — | — | EP | disclosed |
| US-6472348-B1 | Pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2002-10-29 | — | — | US | disclosed |
| US-6265349-B1 | Pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD (JP) | 2001-07-24 | — | — | US | disclosed |
| US-6048823-A | Pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0885885-A1 | PYRIDONE DERIVATIVES AND HERBICIDES | KumaiI Chemical Industry Co., Ltd. (JP) | 1998-12-23 | — | — | EP | disclosed |