Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 3/20 | 0.40 |
| ▸ | S100A4 | P26447 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8347590 | 0.84 | GPR35 (0.47) | AAK1ALDH1A1PTPRCS100A4CA1 | |
| SCHEMBL30298789 | 0.82 | ALDH1A1 (0.49) | AAK1ALDH1A1PTPRCS100A4CA1 | |
| SCHEMBL30292047 | 0.82 | MAPT (0.53) | AAK1ALDH1A1PTPRCS100A4MEN1 | |
| SCHEMBL30292049 | 0.82 | IMPDH2 (0.45) | AAK1ALDH1A1PTPRCS100A4CA1 | |
| SCHEMBL5777364 | 0.82 | IMPDH2 (0.45) | AAK1ALDH1A1PTPRCS100A4CA1 | |
| SCHEMBL6170663 | 0.82 | ALDH1A1 (0.49) | AAK1ALDH1A1PTPRCS100A4CA1 | |
| SCHEMBL6170216 | 0.82 | AAK1 (0.55) | AAK1ALDH1A1PTPRCS100A4CA1 | |
| SCHEMBL6224045 | 0.82 | MAPT (0.53) | AAK1ALDH1A1PTPRCS100A4MEN1 | |
| SCHEMBL16371752 | 0.82 | CYP3A4 (0.45) | AAK1ALDH1A1PTPRCS100A4CA1 | |
| SCHEMBL926287 | 0.79 | HSD17B10 (0.49) | AAK1ALDH1A1PTPRCS100A4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | AAK1 1161/4885ALDH1A1 1541/4885PTPRC 4607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.