Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.30 |
| ▸ | TUBB | P07437 | 1/20 | 0.30 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.30 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.30 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.30 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.30 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.30 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.30 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.30 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.30 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.30 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.30 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.30 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.30 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1201585 | 1.00 | IDH1 (0.32) | IDH1DRD2DRD4TUBB4ATUBB | |
| SCHEMBL1201584 | 0.84 | — | — | |
| SCHEMBL4652962 | 0.81 | LMNA (0.38) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4652963 | 0.81 | LMNA (0.38) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL30177122 | 0.81 | DRD2 (0.32) | IDH1DRD2DRD4TUBB4ATUBB | |
| SCHEMBL275480 | 0.81 | DRD2 (0.32) | IDH1DRD2DRD4TUBB4ATUBB | |
| SCHEMBL18416028 | 0.81 | DRD4 (0.34) | IDH1DRD2DRD4 | |
| SCHEMBL25395218 | 0.80 | IDH1 (0.33) | IDH1DRD2DRD4 | |
| SCHEMBL25395238 | 0.80 | IDH1 (0.33) | IDH1DRD2DRD4 | |
| SCHEMBL30036634 | 0.80 | IDH1 (0.33) | IDH1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286985-B1 | SUBSTITUTED PYRIDINE HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-06-21 | — | — | EP | disclosed |
| EP-1574510-A1 | Substituted pyridine herbicides | Syngenta Participations AG (CH) | 2005-09-14 | — | — | EP | disclosed |
| US-6838564-B2 | Substituted pyridine herbicides | SYNGENTA CROP PROTECTION, INC. (US) | 2005-01-04 | — | — | US | disclosed |