Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.73 |
| ▸ | NPC1 | O15118 | 9/20 | 0.73 |
| ▸ | APP | P05067 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.56 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CLK1 | P49759 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1691409 | 0.85 | RAB9A (1.00) | RAB9ANPC1APPALDH1A1ALDH1A3 | |
| SCHEMBL5775919 | 0.83 | RAB9A (0.81) | RAB9ANPC1APPALDH1A1ALDH1A3 | |
| SCHEMBL5776509 | 0.82 | APP (0.61) | RAB9ANPC1APPALDH1A1ALDH1A3 | |
| SCHEMBL1664803 | 0.81 | RAB9A (0.83) | RAB9ANPC1APPALDH1A1ALDH1A3 | |
| SCHEMBL13217820 | 0.80 | RAB9A (0.81) | RAB9ANPC1APPALDH1A1ALDH1A3 | |
| SCHEMBL13325716 | 0.80 | RAB9A (0.81) | RAB9ANPC1APPALDH1A1ALDH1A3 | |
| SCHEMBL27921746 | 0.79 | NPC1 (0.76) | RAB9ANPC1APPALDH1A1ALDH1A3 | |
| SCHEMBL2404662 | 0.79 | RAB9A (1.00) | RAB9ANPC1APPALDH1A1ALDH1A3 | |
| Bromide SCHEMBL1691853 | 0.78 | ALDH1A1 (0.80) | RAB9ANPC1APPALDH1A1ALDH1A3 | |
| SCHEMBL5776801 | 0.77 | RAB9A (0.65) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | RAB9A 3127/4885NPC1 952/4885APP 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.