Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.37 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.37 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5775613 | 1.00 | NOX1 (0.51) | NOX1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL5777817 | 0.90 | MPO (0.44) | NOX1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL5777819 | 0.90 | MPO (0.44) | NOX1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL5779475 | 0.86 | IMPDH2 (0.36) | NOX1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL5778831 | 0.86 | MPO (0.56) | NOX1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL5778833 | 0.86 | MPO (0.56) | NOX1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL5779782 | 0.81 | LMNA (0.40) | NPC1RAB9AKMT2AMEN1MPO | |
| SCHEMBL5779785 | 0.81 | LMNA (0.40) | NPC1RAB9AKMT2AMEN1MPO | |
| SCHEMBL5779459 | 0.80 | NPC1 (0.46) | NOX1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL5779271 | 0.80 | NPC1 (0.47) | NPC1RAB9AKMT2AMEN1IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | NOX1 1745/4885NPC1 952/4885RAB9A 3127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.