Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20571616 | 0.83 | KAT2B (0.42) | KDM4EALDH1A1GAAKAT2BCCNC | |
| SCHEMBL20571668 | 0.83 | KDM4E (0.41) | KDM4EALDH1A1GAAKAT2BCCNC | |
| SCHEMBL14421587 | 0.83 | KDM4E (0.41) | KDM4EALDH1A1GAAKAT2BCCNC | |
| SCHEMBL29484071 | 0.83 | KDM4E (0.41) | KDM4EALDH1A1GAAKAT2BCCNC | |
| SCHEMBL763192 | 0.81 | KAT2B (0.43) | KDM4EALDH1A1GAAKAT2BMAPT | |
| SCHEMBL20571076 | 0.80 | PTGER4 (0.46) | KDM4EALDH1A1GAAKAT2BCCNC | |
| SCHEMBL4245750 | 0.80 | KDM4E (0.38) | KDM4EALDH1A1GAAKAT2BCCNC | |
| SCHEMBL8252221 | 0.80 | KAT2B (0.42) | KDM4EALDH1A1GAAKAT2BHDAC3 | |
| SCHEMBL4242451 | 0.80 | NCF1 (0.45) | KDM4EALDH1A1GAAKAT2BSLC6A2 | |
| SCHEMBL3070346 | 0.79 | LMNA (0.45) | KDM4EALDH1A1GAAKAT2BLOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326864-B1 | ARYL OR HETEROARYL FUSED IMIDAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | PFIZER PHARMA (JP) | 2006-03-15 | — | — | EP | disclosed |