Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29484071 | 0.90 | KDM4E (0.41) | KAT2BTLR8TLR7ABCB1ABCG2 | |
| SCHEMBL14421587 | 0.90 | KDM4E (0.41) | KAT2BTLR8TLR7ABCB1ABCG2 | |
| SCHEMBL740491 | 0.84 | PTGER4 (0.44) | KAT2BKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL3070346 | 0.83 | LMNA (0.45) | KAT2BKDM4EALDH1A1GAACYP3A4 | |
| SCHEMBL8252221 | 0.83 | KAT2B (0.42) | KAT2BKDM4EALDH1A1GAATSHR | |
| SCHEMBL5776093 | 0.81 | KDM4E (0.41) | KAT2BDRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL20571668 | 0.81 | KDM4E (0.41) | KAT2BKDM4EALDH1A1GAACYP2C19 | |
| SCHEMBL20571616 | 0.81 | KAT2B (0.42) | KAT2BKDM4EALDH1A1GAAMAPT | |
| SCHEMBL20571076 | 0.80 | PTGER4 (0.46) | KAT2BKDM4EALDH1A1GAAMAPT | |
| SCHEMBL4245750 | 0.80 | KDM4E (0.38) | KAT2BDRD2DRD3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |