Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5777302 | 0.87 | TBXA2R (0.33) | TBXA2RPTGDR2 | |
| SCHEMBL5773536 | 0.81 | TBXA2R (0.56) | TBXA2RPTGDR2 | |
| SCHEMBL5776538 | 0.79 | TBXA2R (0.39) | TBXA2RPTGDR2 | |
| SCHEMBL5777733 | 0.76 | TBXA2R (0.42) | TBXA2RPTGDR2 | |
| SCHEMBL5778258 | 0.72 | TBXA2R (0.72) | TBXA2RPTGDR2 | |
| SCHEMBL5778173 | 0.68 | TBXA2R (0.50) | TBXA2RPTGDR2 | |
| SCHEMBL5777307 | 0.66 | TBXA2R (0.32) | TBXA2RPTGDR2 | |
| SCHEMBL6732180 | 0.62 | TBXA2R (0.64) | TBXA2RPTGDR2 | |
| SCHEMBL5773541 | 0.61 | TBXA2R (0.55) | TBXA2RPTGDR2 | |
| SCHEMBL5778238 | 0.61 | TBXA2R (0.72) | TBXA2RPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395590-B1 | DIHYDROPYRROLO¬1,2-A|INDOLE AND TETRAHYDROPYRIDO¬1,2-A|INDOLE DERIVATIVES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | MERCK FROSST CANADA INC (CA) | 2006-09-27 | — | — | EP | disclosed |