Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | UNG | P13051 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ALDH5A1 | P51649 | 2/20 | 0.32 |
| ▸ | ABAT | P80404 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5779948 | 0.88 | ALDH1A1 (0.33) | ALDH1A1RAB9AUNGKDM4EPTGS2 | |
| SCHEMBL5778941 | 0.82 | CYP2A6 (0.38) | ALDH1A1RAB9AKDM4EPTGS2CYP2A6 | |
| SCHEMBL5774633 | 0.82 | ALDH1A1 (0.44) | ALDH1A1ALDH1A3MEN1KMT2AALDH3A1 | |
| SCHEMBL5912956 | 0.81 | HTR2C (0.36) | ALDH1A1 | |
| SCHEMBL1028247 | 0.78 | PRKCI (0.37) | ALDH1A1RAB9AKDM4EPTGS2NPC1 | |
| SCHEMBL1935709 | 0.75 | RAB9A (0.47) | ALDH1A1RAB9ACYP2A6CYP2A13NPC1 | |
| SCHEMBL2724314 | 0.75 | ALDH1A1 (0.41) | ALDH1A1RAB9AKDM4EPTGS2CYP2A6 | |
| SCHEMBL322185 | 0.74 | NPC1 (0.46) | ALDH1A1RAB9AKDM4ENPC1MEN1 | |
| SCHEMBL1026376 | 0.74 | CYP1A2 (0.46) | ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL5912959 | 0.73 | MEN1 (0.36) | ALDH1A1ALDH1A3MEN1KMT2AALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | ALDH1A1 1541/4885RAB9A 3127/4885UNG 4784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.