Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ALDH1A3 | P47895 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5776983 | 0.82 | ALDH1A1 (0.33) | CYP2A6CYP2A13ALDH1A3ALDH1A1ALDH3A1 | |
| SCHEMBL2724314 | 0.81 | ALDH1A1 (0.41) | CYP2A6ALDH1A3ALDH1A1ALDH3A1KDM4E | |
| SCHEMBL18519479 | 0.80 | ALDH1A1 (0.41) | CYP2A6CYP2A13SLC6A2SLC6A4ALDH1A3 | |
| SCHEMBL28007857 | 0.76 | ALDH1A3 (0.49) | CYP2A6CYP2A13ALDH1A3ALDH1A1ALDH3A1 | |
| SCHEMBL7291558 | 0.76 | ALDH1A1 (0.55) | CYP2A6CYP2A13ALDH1A1KDM4ETDP1 | |
| SCHEMBL25273587 | 0.76 | ALDH1A1 (0.58) | ALDH1A3ALDH1A1TDP1MEN1MAPT | |
| SCHEMBL5912956 | 0.76 | HTR2C (0.36) | SLC6A4ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL18281038 | 0.75 | ALDH1A1 (0.53) | CYP2A6CYP2A13ALDH1A1KDM4ETDP1 | |
| SCHEMBL28818187 | 0.75 | KIF11 (0.41) | CYP2A6CYP2A13SLC6A2SLC6A4ALDH1A3 | |
| SCHEMBL5915441 | 0.74 | ALDH1A1 (0.59) | ALDH1A1CYP1A2CYP2C19TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | CYP2A6 2679/4885CYP2A13 1390/4885SLC6A2 3242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.