Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9029404 | 0.89 | HTT (0.37) | ALDH1A1MAPTRAB9ANPC1MEN1 | |
| SCHEMBL23796408 | 0.87 | ALDH1A1 (0.39) | ALDH1A1MAPTRAB9ANPC1MEN1 | |
| SCHEMBL23795980 | 0.87 | CYP1A2 (0.37) | ALDH1A1MAPTRAB9ANPC1MEN1 | |
| SCHEMBL23796111 | 0.81 | CYP1A2 (0.33) | ALDH1A1MAPTRAB9ANPC1MEN1 | |
| SCHEMBL22578954 | 0.79 | CYP1A2 (0.43) | ALDH1A1MAPTRAB9ANPC1MEN1 | |
| SCHEMBL29117128 | 0.76 | LMNA (0.43) | ALDH1A1MAPTRAB9ANPC1MEN1 | |
| SCHEMBL29117129 | 0.76 | LMNA (0.43) | ALDH1A1MAPTRAB9ANPC1MEN1 | |
| SCHEMBL25219857 | 0.76 | CYP1A2 (0.41) | ALDH1A1MAPTRAB9ANPC1MEN1 | |
| SCHEMBL18039508 | 0.76 | CYP1A2 (0.41) | ALDH1A1MAPTRAB9ANPC1MEN1 | |
| SCHEMBL23796030 | 0.75 | CYP1A2 (0.40) | ALDH1A1MAPTRAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1652839-A2 | Drug efflux pump inhibitor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-05-03 | — | — | EP | disclosed |
| EP-1227084-B1 | DRUG DISCHARGE PUMP INHIBITORS | TRINE PHARMACEUTICALS INC (US) | 2005-12-14 | — | — | EP | disclosed |
| EP-1227084-A1 | DRUG DISCHARGE PUMP INHIBITORS | Microcide Pharmaceuticals, Inc. (US) | 2002-07-31 | — | — | EP | disclosed |
| US-5583092-A | PLANT ANTIGROWTH AGENTS | AMERICAN CYANAMID COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0726261-A1 | Herbidical 1,2,4 thiadiazoles | American Cyanamid Company (US) | 1996-08-14 | — | — | EP | disclosed |
| EP-0726260-A1 | Herbicidal (1,2,4)thiadiazoles | AMERICAN CYANAMID COMPANY (US) | 1996-08-14 | — | — | EP | disclosed |