Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5777601 | 0.89 | ALDH1A1 (0.40) | LMNAPOLBALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL23795980 | 0.77 | CYP1A2 (0.37) | HTTLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL23796408 | 0.77 | ALDH1A1 (0.39) | HTTLMNAPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL9028859 | 0.73 | MAPT (0.54) | LMNAPOLBALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL23796111 | 0.72 | CYP1A2 (0.33) | HTTLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL22578954 | 0.70 | CYP1A2 (0.43) | LMNAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL43934 | 0.69 | — | — | |
| SCHEMBL12370927 | 0.68 | EGFR (0.32) | — | |
| SCHEMBL29117129 | 0.68 | LMNA (0.43) | LMNAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL29117128 | 0.68 | LMNA (0.43) | LMNAALDH1A1SMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726261-A1 | Herbidical 1,2,4 thiadiazoles | American Cyanamid Company (US) | 1996-08-14 | — | — | EP | disclosed |