Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | WDR5 | P61964 | 11/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3440357 | 0.84 | LMNA (0.67) | LMNAALDH1A1WDR5NPC1RAB9A | |
| SCHEMBL5308466 | 0.84 | ALDH1A1 (0.70) | LMNAALDH1A1WDR5NPC1RAB9A | |
| SCHEMBL9698908 | 0.84 | LMNA (0.70) | LMNAALDH1A1WDR5NPC1RAB9A | |
| SCHEMBL4839937 | 0.83 | WDR5 (0.90) | LMNAALDH1A1WDR5NPC1RAB9A | |
| SCHEMBL5778502 | 0.83 | LMNA (0.65) | LMNAALDH1A1WDR5NPC1RAB9A | |
| SCHEMBL24517436 | 0.83 | NPC1 (0.88) | LMNAALDH1A1WDR5NPC1RAB9A | |
| SCHEMBL18281469 | 0.83 | LMNA (0.94) | LMNAALDH1A1WDR5NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5300777 | 0.81 | LMNA (0.97) | LMNAALDH1A1WDR5NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5379554 | 0.81 | LMNA (0.70) | LMNAALDH1A1WDR5NPC1RAB9A | |
| SCHEMBL20514707 | 0.80 | ALDH1A1 (0.65) | LMNAALDH1A1WDR5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | LMNA 861/4885ALDH1A1 1541/4885WDR5 635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.