Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | VHL | P40337 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | HPN | P05981 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15110028 | 0.89 | NAMPT (0.50) | NAMPTHDAC1HDAC6VHLGPR119 | |
| SCHEMBL5778056 | 0.79 | HDAC1 (0.43) | NAMPTHDAC1HDAC6VHLGPR119 | |
| SCHEMBL5777062 | 0.76 | NPC1 (0.44) | HDAC1GPR119ACACBKDM4ENPC1 | |
| SCHEMBL5775952 | 0.74 | NPC1 (0.49) | HDAC1IMPDH2IMPDH1KDM4ENPC1 | |
| SCHEMBL5778725 | 0.73 | KDM4E (0.48) | HDAC6ATRIMPDH2IMPDH1KCNJ1 | |
| SCHEMBL16915211 | 0.73 | IMPDH2 (0.51) | GPR119IMPDH2IMPDH1KDM4ENPC1 | |
| SCHEMBL29726474 | 0.73 | GRM2 (0.44) | NAMPTGPR119IMPDH2IMPDH1L3MBTL1 | |
| SCHEMBL5779456 | 0.72 | GPR119 (0.45) | GPR119IMPDH2IMPDH1KDM4ENPC1 | |
| SCHEMBL25255179 | 0.72 | NAMPT (0.43) | NAMPTGPR119IMPDH2IMPDH1L3MBTL1 | |
| SCHEMBL15110902 | 0.71 | VHL (0.54) | HDAC1VHLIMPDH2IMPDH1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | NAMPT 4589/4885HDAC1 64/4885HDAC6 351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.