Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.42 |
| ▸ | IMPDH1 | P20839 | 3/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | VHL | P40337 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15110028 | 0.86 | NAMPT (0.50) | HDAC1HDAC6IMPDH2IMPDH1NAMPT | |
| SCHEMBL5779933 | 0.85 | NPC1 (0.44) | IMPDH2IMPDH1VHLRAB9ANPC1 | |
| SCHEMBL5779930 | 0.85 | NPC1 (0.44) | IMPDH2IMPDH1VHLRAB9ANPC1 | |
| SCHEMBL5779773 | 0.81 | LMNA (0.40) | IMPDH2IMPDH1VHLRAB9ANPC1 | |
| SCHEMBL5779771 | 0.81 | LMNA (0.40) | IMPDH2IMPDH1VHLRAB9ANPC1 | |
| SCHEMBL5777066 | 0.79 | NPC1 (0.46) | IMPDH2IMPDH1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5778053 | 0.79 | NAMPT (0.47) | HDAC1HDAC6IMPDH2IMPDH1NAMPT | |
| SCHEMBL5775270 | 0.78 | NPC1 (0.42) | IMPDH2IMPDH1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5777534 | 0.78 | IMPDH2 (0.41) | IMPDH2IMPDH1VHLGPR119RAB9A | |
| SCHEMBL5775267 | 0.78 | NPC1 (0.42) | IMPDH2IMPDH1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | HDAC1 64/4885HDAC6 351/4885IMPDH2 4694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.