Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | OGG1 | O15527 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13299291 | 0.79 | KEAP1 (0.44) | ALOX5ALDH1A1CES2CES1SMN1; SMN2 | |
| SCHEMBL323295 | 0.79 | LMNA (0.62) | CYP1A2ALOX5CES2CES1SMN1; SMN2 | |
| SCHEMBL503470 | 0.79 | LMNA (0.62) | CYP1A2ALOX5CES2CES1SMN1; SMN2 | |
| SCHEMBL17377318 | 0.79 | ESR1 (0.52) | CYP1A2KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10932275 | 0.79 | ESR1 (0.52) | CYP1A2KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL14464110 | 0.79 | KEAP1 (0.44) | ALOX5ALDH1A1CES2CES1SMN1; SMN2 | |
| SCHEMBL4146178 | 0.79 | CYP1A2 (0.57) | CYP1A2ALOX5CES2CES1SMN1; SMN2 | |
| SCHEMBL17377207 | 0.79 | ESR1 (0.52) | CYP1A2KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29903941 | 0.79 | LMNA (0.62) | CYP1A2ALOX5CES2CES1SMN1; SMN2 | |
| SCHEMBL10170603 | 0.79 | LMNA (0.62) | CYP1A2ALOX5CES2CES1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397353-B1 | 2-(2,6-DISUBSTITUTED PHENYL)-4-ARYL-5-ALKYL-1,3-OXAZOLINE COMPOUNDS USEFUL AS INSECTICIDES AND ACARICIDES | DOW AGROSCIENCES LLC (US) | 2006-10-25 | — | — | EP | disclosed |
| EP-1397353-A1 | 2-(2,6-DISUBSTITUTED PHENYL)-4-ARYL-5-ALKYL-1,3-OXAZOLINE COMPOUNDS USEFUL AS INSECTICIDES AND ACARICIDES | Dow Agrosciences LLC (US) | 2004-03-17 | — | — | EP | disclosed |
| US-6573286-B1 | Oxazoline compounds having a 2,6-disubstituted-phenyl group in the 2-position, an aryl or heteroaryl group in the 4-position and an alkyl group in the 5-position are effective in controlling aphids, insects and mites. | DOW AGROSCIENCES LLC | 2003-06-03 | — | — | US | disclosed |
| WO-2003000669-A1 | 2-(2,6-DISUBSTITUTED PHENYL)-4-ARYL-5-ALKYL-1,3-OXAZOLINE COMPOUNDS USEFUL AS INSECTICIDES AND ACARICIDES | DOW AGROSCIENCES LLC (US) | 2003-01-03 | — | — | WO | disclosed |
| US-5405860-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-04-11 | — | — | US | disclosed |
| US-4912122-A | Triazolyl alkanones or triazolyl-alkanols | BAYER AKTIENGESELLSCHAFT (DE) | 1990-03-27 | — | — | US | disclosed |
| US-4776877-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1988-10-11 | — | — | US | disclosed |
| US-4772623-A | FUNGICIDES, MICROBIOCIDES, PLANT GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-20 | — | — | US | disclosed |
| US-4582843-A | FUNGICIDES, MICROBIOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1986-04-15 | — | — | US | disclosed |