SCHEMBL4146178

SCHEMBL4146178

CC(=O)C(c1ccc(Br)cc1)c1ccc(Br)cc1

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.57
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
ALOX5 P09917 1/20 0.46
S1PR3 Q99500 1/20 0.44
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
CNR1 P21554 3/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CYP2C19 P33261 1/20 0.41
POLB P06746 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CNR2 P34972 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16807292 0.92 ALDH1A1 (0.52) CYP1A2MEN1KMT2AALOX5S1PR3
SCHEMBL6691326 0.92 KMT2A (0.56) CYP1A2MEN1KMT2AS1PR3CNR1
SCHEMBL5559079 0.79 CYP1A2 (0.55) CYP1A2ALOX5CES2CES1CNR1
SCHEMBL5778110 0.79 CYP1A2 (0.55) CYP1A2ALOX5CES2CES1CNR1
SCHEMBL12280124 0.79 CYP1A2 (0.55) CYP1A2ALOX5CES2CES1SMN1; SMN2
SCHEMBL13424144 0.78 ESR1 (0.53) CYP1A2MEN1KMT2ACNR1CYP2C19
SCHEMBL29450370 0.78 KMT2A (0.52) CYP1A2MEN1KMT2AALOX5S1PR3
SCHEMBL8784244 0.77 CYP1A2 (0.53) CYP1A2ALOX5CES2CES1CNR1
SCHEMBL3993015 0.77 CYP1A2 (0.53) CYP1A2ALOX5CES2CES1CNR1
SCHEMBL6859146 0.77 CYP1A2 (0.53) CYP1A2ALOX5CES2CES1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1993992-B1 TETRAPHENYLNAPHTHALENE DERIVATIVES AND ORGANIC LIGHT EMITTING DIODE USING THE SAME LG CHEMICAL LTD (KR) 2014-11-26 EP disclosed
US-8329316-B2 Tetraphenylnaphalene derivatives and organic light emitting diode using the same LG CHEM, LTD. (KR) 2012-12-11 US disclosed
US-20090174312-A1 Tetraphenylnaphalene Derivatives and Organic Light Emitting Diode Using the Same LG CHEM, LTD. (KR) 2009-07-09 US disclosed
EP-1993992-A1 TETRAPHENYLNAPHTHALENE DERIVATIVES AND ORGANIC LIGHT EMITTING DIODE USING THE SAME LG Chem, Ltd. (KR) 2008-11-26 EP disclosed
WO-2007105884-A1 TETRAPHENYLNAPHTHALENE DERIVATIVES AND ORGANIC LIGHT EMITTING DIODE USING THE SAME LG CHEM, LTD. (KR) 2007-09-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090174312-A1 Tetraphenylnaphalene Derivatives and Organic Light Emitting Diode Using the Same CRY2, CRY1, PPOX CYP1A2 2196/4885MEN1 526/4885KMT2A 2050/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.