Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CBLB | Q13191 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5780374 | 0.79 | DRD2 (0.42) | RAB9AJAK2JAK1TYK2JAK3 | |
| SCHEMBL5778158 | 0.79 | CACNA2D1 (0.39) | RAB9A | |
| SCHEMBL5783601 | 0.78 | SLC6A2 (0.36) | SLC6A2SLC6A4DRD2DRD4DRD3 | |
| SCHEMBL5783597 | 0.74 | DRD2 (0.41) | DRD2DRD4DRD3 | |
| SCHEMBL5800036 | 0.74 | RAB9A (0.34) | RAB9ACBLBJAK2JAK1TYK2 | |
| SCHEMBL5784278 | 0.74 | DRD2 (0.42) | RAB9AJAK2JAK1TYK2JAK3 | |
| SCHEMBL5781204 | 0.74 | DRD2 (0.38) | JAK2JAK1TYK2JAK3DRD2 | |
| SCHEMBL5781228 | 0.74 | CCR3 (0.43) | — | |
| SCHEMBL5783782 | 0.72 | DCPS (0.36) | JAK2JAK1TYK2JAK3DRD2 | |
| SCHEMBL5782499 | 0.72 | DRD2 (0.47) | L3MBTL1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254904-B1 | NOVEL PIPERIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME | EISAI CO LTD (JP) | 2006-05-24 | — | — | EP | disclosed |